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high-blood-pressure Clinical Trials

A listing of high-blood-pressure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 895 clinical trials
K Kay Ryan, PharmD

Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence

Socioeconomically disadvantaged populations with multiple chronic conditions have high rates of nonadherence to essential chronic disease medications after hospital discharge. Medication nonadherence after hospital discharge is significantly associated with increased mortality and higher rates of readmissions and costs among these patients. Major patient-reported barriers to essential medication use after hospital …

18 years of age All Phase N/A
C Catherine Avitabile, MD

iTONE Trial (exercIse Training in pulmONary hypertEnsion) Exercise Program for Pediatric PH

Children with pulmonary hypertension (PH) engage in less physical activity than their peers. This is a concern since adult data support exercise as a non-pharmacologic treatment for PH. Despite adult data, therapeutic exercise has not been widely adopted in pediatric PH. Investigators have previously demonstrated that children with PH have …

8 - 18 years of age All Phase N/A
Y Yifei Huang, MD

3D-MRE for Assessing Cirrhosis, Advanced Chronic Liver Disease and Portal Hypertension

How to construct a novel, non-invasive, accurate, and convenient method to achieve prediction of hepatic venous pressure gradient (HVPG) is an important general problem in the management of portal hypertension in cirrhosis or advanced chronic liver disease. We plan to investigate the ability of three demensional-magnetic resonance elastography (3D-MRE) to …

18 - 75 years of age All Phase N/A
M Mark Reinhard, MD, PhD

A Prospective Danish National Registry of PTRA in Patients With Renovascular Hypertension

A prospective Danish national registry of percutaneous transluminal renal angioplasty (PTRA) in high-risk patients with renal artery stenosis selected on the basis of common national criteria, and with a common follow-up protocol for all three Danish centres offering PTRA

years of age All Phase N/A

Induced Hypertension in Acute PRogrESsive Perforating Artery Stroke Using Peripheral Dilute noREpinephrine

PRESSURE is a multicenter, prospective, randomized, open, blinded end-point assessed (PROBE) trial, that aims to evaluate the efficacy and safety of drug-induced hypertension using peripheral dilute norepinephrine, in patients with acute ischemic stroke in a perforating artery territory and experiencing early neurological deterioration.

18 years of age All Phase 3
F Fei Gao, PhD, MD

TIPS Plus Half-dose Donafenib in AHCC with PVTT-associated Portal Hypertension

The purpose of this study is to evaluate the efficacy and safety of transjugular intrahepatic portosystemic shunt (TIPS) plus half-dose donafenib (a kind of anti-angiogenesis agents) in advanced hepatocellular carcinoma (BCLC-C Stage) accompanied by tumor thrombosis-associated portal hypertension.

18 - 75 years of age All Phase 2
A Aya Ali Amin

Search About Contributing Factors That Leading to Intradialytic Hypertension in Hemodialysis Patients

The aim of this study is searching about contributing factors that leading to intradialytic hypertension in hemodialysis patients more than 18 years old in hemodialysis unit at sohag University hospitals

18 - 70 years of age All Phase N/A
Y Yifei Dong, doctorate

Superselective Adrenal Arterial Embolization for Refractory Hypertension: A Proof-of-Concept Study

The subjects of this study were patients with essential refractory hypertension. The purpose of this study is to evaluate the safety and efficacy of superselective adrenal arterial embolization (SAAE) in patients with primary refractory hypertension and to explore the possibility of SAAE in patients with primary refractory hypertension.After the subject …

18 years of age All Phase N/A
R Recruitment Department

A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

The goal of this clinical trial is to learn if the drug RT-001 works to reduce high blood pressure (hypertension) in adults. It will also learn about the safety of RTN-001. The main questions it aims to answer are: Does RTN-001 lower blood pressure in patients who have uncontrolled hypertension? …

18 - 70 years of age All Phase 2
J Jorge Martinez-Solano, MD, PhD

Evaluation of the BMPR2-Activin Signaling Pathway in Group II Pulmonary Hypertension.

Previous data from our group showed reduced BMPR2 isoform A in pulmonary hypertension associated with left heart disease (PH-LHD) of valvular origin. Focusing on dysregulation of the BMPR2-activin pathway, a key regulator of vascular homeostasis, this project uses a multimodal approach combining molecular biology, advanced cardiac imaging, and histology. Its …

18 years of age All Phase N/A

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