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high-blood-pressure Clinical Trials

A listing of high-blood-pressure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 914 clinical trials
L Ludivine Lebourg, Dr

Endothelin-1 Receptor Blockade in Resistant Hypertension

The management of patients with resistant arterial hypertension, who are characterized by a very high cardiovascular risk, remains a major therapeutic issue. The use of endothelin-1 (ET-1) receptor antagonists, in addition to lowering blood pressure, may also improve endothelial function in these patients. The objective of this study is to …

18 - 80 years of age All Phase 2
S Ségolène TURQUIER

Exploration of Metabolome in Patients With Interstitial Lung Disease and Pulmonary Hypertension With or Without Specific Pulmonary Hypertension Treatment

Fibrosing interstitial lung diseases (FILDs) encompass a group of rare diseases characterized by progressive pulmonary fibrosis leading to respiratory failure. Current treatments primarily aim to slow disease progression but remain limited, making lung transplantation the ultimate recourse. The development of pulmonary hypertension (PH) in the context of FILDs significantly worsens …

18 years of age All Phase N/A
M Marcelo BP Amato, MD, PhD

Electrical Impedance Tomography for Assessment of Pulmonary Hypertension

Pulmonary hypertension is a serious and progressive disease that is difficult to treat and diagnose, mainly because its symptoms are nonspecific and often delay recognition. Early diagnosis is a major challenge. Although several tests may suggest the disease, the definitive diagnosis still requires right heart catheterization, an invasive procedure that …

18 years of age All Phase N/A
Q Qian Wang, PHD

Basic and Clinical Research of Pregnancy-Induced Hypertension

Collect blood pressure, blood, amniotic fluid, placenta and other samples from normal pregnant women, patients with pregnancy-induced hypertension and those who have experienced miscarriage, and conduct tests on them.

20 - 50 years of age Female Phase N/A
L Lecarpentier Edouard, MD

Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy

A randomized clinical trial to assess the efficiency of acetylsalicylic acid (aspirin) 150 mg/day started before 20 weeks of gestation in the prevention on maternal and fœtal complications in pregnant women with chronic hypertension.

18 years of age Female Phase 3
V Victoria Jauk

Chronic Hypertension and Pregnancy 2 (CHAP2) Pilot Project

The CHAP2 study is designed to provide preliminary data for a larger multicenter study to assess whether treatment of stage 1 hypertension (HTN) in pregnancy improves maternal and or neonatal outcomes. The primary objective of this pilot study is to determine if anti-HTN treatment to BP\<130/80mmHg in pregnant patients with …

14 - 89 years of age Female Phase 1
A Amelie ya

Stenting Versus Neurosurgical Treatment of Idiopathic Intracranial Hypertension.

Idiopathic intracranial hypertension (HTICi) is a pathology, affecting young adults with a predominance of women, due to an increase in intracranial pressure, which may be associated with stenosis of the cerebral venous sinuses and whose origin remains unknown. This hypertension can lead to papillary edema (OP) which can lead to …

18 years of age All Phase N/A
E Emily C Smith, RN MPH

Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic hypotension. The purpose of this study is to assess whether continuous positive airway pressure (CPAP) decreases blood pressure in autonomic failure patients …

18 - 85 years of age All Phase N/A
G Galina V Schelkova

Registry of Patients With chrOnic thromboemboLic Pulmonary hypErTension

The goal of this observational study is to gather information on background, medical history, symptoms and physical condition, treatment options of people with chronic thromboembolic pulmonary hypertension in real clinical practice in Russia. The main question it aims to answer is: Which factors most influence the prognosis of participants?

18 years of age All Phase N/A
P Patrick Schoettker, Assoc Prof

Smartphone Blood Pressure Measurement to Screen for Hypertension

The goal of this observational study is to assess the feasibility of classifying people whose blood pressures are within hypertensive range using a machine-learning approach based on features derived from smartphone video data recorded at the patient's fingertips. The main question\[s\] it aims to answer are: Is a smartphone a …

18 - 80 years of age All Phase N/A

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