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high-blood-pressure Clinical Trials

A listing of high-blood-pressure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 904 clinical trials
A Amelie ya

Stenting Versus Neurosurgical Treatment of Idiopathic Intracranial Hypertension.

Idiopathic intracranial hypertension (HTICi) is a pathology, affecting young adults with a predominance of women, due to an increase in intracranial pressure, which may be associated with stenosis of the cerebral venous sinuses and whose origin remains unknown. This hypertension can lead to papillary edema (OP) which can lead to …

18 years of age All Phase N/A
E Emily C Smith, RN MPH

Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic hypotension. The purpose of this study is to assess whether continuous positive airway pressure (CPAP) decreases blood pressure in autonomic failure patients …

18 - 85 years of age All Phase N/A
G Galina V Schelkova

Registry of Patients With chrOnic thromboemboLic Pulmonary hypErTension

The goal of this observational study is to gather information on background, medical history, symptoms and physical condition, treatment options of people with chronic thromboembolic pulmonary hypertension in real clinical practice in Russia. The main question it aims to answer is: Which factors most influence the prognosis of participants?

18 years of age All Phase N/A
P Patrick Schoettker, Assoc Prof

Smartphone Blood Pressure Measurement to Screen for Hypertension

The goal of this observational study is to assess the feasibility of classifying people whose blood pressures are within hypertensive range using a machine-learning approach based on features derived from smartphone video data recorded at the patient's fingertips. The main question\[s\] it aims to answer are: Is a smartphone a …

18 - 80 years of age All Phase N/A
D Dr Fatima

Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis

The APIXABAN-PK trial is a prospective, randomized, single-blind, placebo-controlled study designed to evaluate the efficacy and safety of apixaban in combination with carvedilol versus placebo with carvedilol in preventing portal hypertension-related complications in patients with cirrhosis. Conducted at the Gastroenterology and Hepatology Department and Clinical Trials Unit (CTU) of Asian …

18 years of age All Phase 4

Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT)

Pulmonary hypertension secondary to left heart disease is associated with increased morbidity and mortality, particularly in patients with rheumatic chronic valvular heart disease, which remains highly prevalent in low- and middle-income countries. These patients often present late with severe pulmonary hypertension, limiting surgical options and worsening outcomes. Sildenafil, a phosphodiesterase-5 …

18 years of age All Phase 2/3
C Colm Travers, MD

Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants

Around 50% of infants born extremely preterm develop a chronic lung disease known as bronchopulmonary dysplasia of which some infants will also develop pulmonary hypertension of which 50% of children will die before the age of 2. Physicians are currently limited in their ability to select the most appropriate oxygen …

1 - 5 years of age All Phase N/A

Real World Observational Study of Sotatercept for Pulmonary Hypertension

The purpose of this study seeks to describe the real world initial experience with sotatercept in the treatment of pulmonary hypertension.

18 years of age All Phase N/A
Y Yuxi Li, MD

Fractional Flow Reserve to Determine Atherosclerosis Renovascular Hypertension Stenting

Although randomized trials have demonstrated there is no benefit of renal-artery stenting in addition to medical therapy for patients with atherosclerosis renal artery stenosis, many patients indeed gained benefit in daily practices after stenting, such as reduction in blood pressure and recovery in renal functions. One important gap is that …

18 years of age All Phase N/A
J Juanni Gong

Study on the Treatment of Nonthrombotic Obstructive Pulmonary Hypertension

Through a randomized controlled trial (RCT) design, this study aiming to evaluated the efficacy and safety of rituximab lymph node injection combined with pulmonary vascular interventional therapy in treating fibrosing mediastinal pulmonary hypertension (FM-PH).Eligible participants were randomly assigned to either the combined treatment group, receiving both pulmonary vascular intervention and …

18 - 85 years of age All Phase N/A

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