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high-blood-pressure Clinical Trials

A listing of high-blood-pressure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 914 clinical trials
M Mark Reinhard, MD, PhD

A Prospective Danish National Registry of PTRA in Patients With Renovascular Hypertension

A prospective Danish national registry of percutaneous transluminal renal angioplasty (PTRA) in high-risk patients with renal artery stenosis selected on the basis of common national criteria, and with a common follow-up protocol for all three Danish centres offering PTRA

years of age All Phase N/A

Induced Hypertension in Acute PRogrESsive Perforating Artery Stroke Using Peripheral Dilute noREpinephrine

PRESSURE is a multicenter, prospective, randomized, open, blinded end-point assessed (PROBE) trial, that aims to evaluate the efficacy and safety of drug-induced hypertension using peripheral dilute norepinephrine, in patients with acute ischemic stroke in a perforating artery territory and experiencing early neurological deterioration.

18 years of age All Phase 3
F Fei Gao, PhD, MD

TIPS Plus Half-dose Donafenib in AHCC with PVTT-associated Portal Hypertension

The purpose of this study is to evaluate the efficacy and safety of transjugular intrahepatic portosystemic shunt (TIPS) plus half-dose donafenib (a kind of anti-angiogenesis agents) in advanced hepatocellular carcinoma (BCLC-C Stage) accompanied by tumor thrombosis-associated portal hypertension.

18 - 75 years of age All Phase 2
A Aya Ali Amin

Search About Contributing Factors That Leading to Intradialytic Hypertension in Hemodialysis Patients

The aim of this study is searching about contributing factors that leading to intradialytic hypertension in hemodialysis patients more than 18 years old in hemodialysis unit at sohag University hospitals

18 - 70 years of age All Phase N/A
Y Yifei Dong, doctorate

Superselective Adrenal Arterial Embolization for Refractory Hypertension: A Proof-of-Concept Study

The subjects of this study were patients with essential refractory hypertension. The purpose of this study is to evaluate the safety and efficacy of superselective adrenal arterial embolization (SAAE) in patients with primary refractory hypertension and to explore the possibility of SAAE in patients with primary refractory hypertension.After the subject …

18 years of age All Phase N/A
R Recruitment Department

A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

The goal of this clinical trial is to learn if the drug RT-001 works to reduce high blood pressure (hypertension) in adults. It will also learn about the safety of RTN-001. The main questions it aims to answer are: Does RTN-001 lower blood pressure in patients who have uncontrolled hypertension? …

18 - 70 years of age All Phase 2
J Jorge Martinez-Solano, MD, PhD

Evaluation of the BMPR2-Activin Signaling Pathway in Group II Pulmonary Hypertension.

Previous data from our group showed reduced BMPR2 isoform A in pulmonary hypertension associated with left heart disease (PH-LHD) of valvular origin. Focusing on dysregulation of the BMPR2-activin pathway, a key regulator of vascular homeostasis, this project uses a multimodal approach combining molecular biology, advanced cardiac imaging, and histology. Its …

18 years of age All Phase N/A

PTGS1 Genetic Variation and Increased Risk for Persistent Pulmonary Hypertension of the Newborn

The purpose of this study is to determine if normally occurring variations in a specific gene called PTGS-1 are associated with an increased risk of narrowing of the ductus arteriosus from exposure to over-the-counter pain medicines (NSAIDs).

- 12 years of age All Phase N/A
Y Yi Yang

Effects of Remote Ischemic Conditioning on Blood Pressure in Older Patients With Hypertension

The purpose of this study is to learn about effects of remote ischemic conditioning on blood pressure in older patients with essential hypertension.

65 - 85 years of age All Phase N/A
A Anlu Wang, Doctor

Efficacy of Songling Xuemaikang Capsules on Grade 1 Hypertension: a Randomized Controlled Trial

The purpose of this study is: To evaluate the efficacy of Songling Xuemaikang Capsules(SLXMKC) with grade 1 hypertension. To reveal the potiential effects of SLXMKC on vascular function and structure of patients with grade 1 hypertension. To explore the underlying mechanisms of the therapeutic effects of SLXMKC on the intervention …

35 - 65 years of age All Phase 4

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