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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,855 clinical trials
W Whitney Cabral

Project 4: ACHIEVE PATHFINDER

ACHIEVE-P4: PATHFINDER is a randomized, blinded clinical trial of portable air cleaners (PAC) provided at the time of hospital discharge to Heart Failure (HF) patients. It will be carried out at Henry Ford Hospitals. This project is part of the ACHIEVE GREATER (Addressing Cardiometabolic Health In Populations Through Early PreVEntion …

18 years of age All Phase N/A
H Hung-Jui Chuang, MD

The Effect of a Smartphone-assisted Hybrid Cardiac Rehabilitation Program in Patients With Heart Failure.

The aim of this randomized controlled trial is to compare the impact of a case manager-led smartphone-assisted hybrid cardiac rehabilitation program with usual care in patients with HF. Participants will undergo a 12-week program led by a case manager and assisted by a smartphone. The study aims to answer two …

18 - 80 years of age All Phase N/A
M Muhammad Iqbal Tariq, PhD*

Eccentric Resistance Training Among Individuals With Chronic Heart Failure

To determine the effects of eccentric resistive training on ventricle functions and aerobic capacity as compared to a resistance and aerobic training among Heart failure (HF)

18 years of age All Phase N/A
J Julian Ormerod

Physiological Versus Right Ventricular Outcome Trial Evaluated for Bradycardia Treatment Upgrades

Guidelines for patients having first-time implants advocate that even when heart function is only mildly impaired, modern pacing approaches should be utilised to avoid the potentially damaging effects of RV pacing to preventing symptoms from pacing induced or worsened cardiomyopathy. However, once a traditional (RV) pacemaker is implanted, development of …

18 years of age All Phase N/A

Utility of Some Novel Biomarkers of Patients With Chronic Heart Failure

Clinical and Economic study of some new biomarkers in chronic heart failure.

18 - 75 years of age All Phase N/A
M Morten Lamberts, MD, PhD

Remote Monitoring of Cardiac Mechanics in Heart Failure Patients

Heart failure is a severe heart disease, where the heart's ability to pump blood is unsatisfactory. The consequence is a high risk of hospitalization and death. Heart failure is treated with medicine which relieves symptoms and slows down the disease progression. This medical treatment needs routine adjustment, but in many …

18 - 90 years of age All Phase N/A
J Joe Cuthbert, MBBS MD

Preparatory Work for a Trial of Adjuncts to Diuretic Treatment in Patients Hospitalised With Heart Failure: Addressing Uncertainties and Building Consensus

Aims and Objectives Choose which adjunctive therapies, at what dose, and for how long Choose the dose(s) of IV furosemide to be used as the comparator Choose primary and secondary outcomes Estimate recruitment and engage sites for a future trial Work package 2a methods overview An online survey of clinicians …

18 years of age All Phase N/A
R Rémi SABATIER, MD

EXPLORATORY STUDY OF THE MYHEARTSENTINEL SYSTEM, A CARDIAMETRICS MEDICAL DEVICE

Background Chronic heart failure represents a major public health challenge, affecting approximately 64 million people worldwide and generating high costs in terms of mortality, frequent hospitalizations, and medical expenses. In France, this disease is expected to cause nearly 70,000 deaths and 181,000 hospital admissions in 2022. Current management, based on …

18 - 90 years of age All Phase N/A

A Research Study on the Effects of NNC0537-1482 in Participants With Heart Failure

The study is testing a new drug (NNC0537-1482) to potentially treat people with heart failure. The purpose of the study is to see if NNC0537-1482 is safe and how it works in the body. Participants will either get NNC0537-1482 or placebo (a "dummy drug" without any active ingredients) and which …

40 - 75 years of age All Phase 1
J Julia González González

Effect of Acetazolamide on Diuresis and Natriuresis in Patients With Acute Heart Failure (SANDI STUDY)

The goal of this observational study is to assess the natriuretic effect of intravenous acetazolamide in patients admitted with heart failure and persistent congestion despite treatment with intravenous furosemide and sodium-glucose cotransporter type 2 (iSGLT2) inhibitors. The main question it aims to answer is whether there is a difference in …

years of age All Phase N/A

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