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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,855 clinical trials
B Bo Jiang

HARMONY Trial : To Evaluate a Therapeutic and Monitoring Device(NOVAtria System) for Heart Failure Management

The objective of the HARMONY trial is to evaluate the safety and efficacy of implantable left atrial pressure sensor and interatrial shunt system for the treatment of chronic heart failure with reduced left ventricular ejection fraction (HFrEF, EF ≤ 40%) and New York Heart Association(NYHA) functional Class II or Class …

18 years of age All Phase N/A
T Tianbao Dr. Yao, MD

Feasibility Study of Diaphragm Synchronized Pacing (DSP) Via the Left Inferior Phrenic Vein (LIPV) Approach

Cardiac resynchronization therapy(CRT) benefits a portion of patients, while more patients are not yet indicated to a therapy that mechanically helps the heart systole and/or diastole. Synchronized diaphragmatic pacing may be feasible to induce diaphragm local contraction and recoil that enhance pump function of the heart, thus improve cardiac function …

18 years of age All Phase N/A

AI-Guided Left Bundle Branch Area Pacing

The purpose of this study is to compare the effectiveness of AI-guided LBBAP versus conventional LBBAP (not AI-guided) in improving CRT response rates and clinical outcomes.

18 years of age All Phase N/A
V Veena Rao

Unmitigated Aldosterone Signaling During Standard Clinical MRA Dosing

The purpose of this research study is to understand the biology related to the potential shortcomings of existing anti-aldosterone therapy.

18 years of age All Phase 4
C Cindy Hall

A Feasibility Study Implant of the WiSE® CRT System With an Intracardiac Pacemaker to Achieve Totally Leadless CRT

Assess the safety and efficacy of the co-implantation of the WiSE CRT System with an intracardiac pacemaker to provide totally leadless CRT.

22 years of age All Phase N/A
G Giovanni Luca Botto, MD

heaRtInsiGHT Alert guIDE: RightAIDE Application of the HeartInsight Acute Heart Failure Predictor in Routine Clinical Practice: Organizational Models and Workflow.

The RightAIDE study is a prospective, multicenter, observational registry designed to evaluate the real-world application of the HeartInsight™ algorithm for predicting acute heart failure (HF) events in patients implanted with a Biotronik ICD or CRT-D device with atrial sensing and Home Monitoring capability. Heart failure is a growing public health …

18 years of age All Phase N/A
M Mansoura University Hospital

Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF

This study looks at people with heart failure who are admitted to the hospital. The goal of the study is to understand whether taking a heart failure medicine called angiotensin receptor-neprilysin inhibitor (ARNI) before hospital admission affects short-term health outcomes. The study will compare two groups of participants: those who …

18 years of age All Phase N/A
R Ruwanthi J Perera

The WiSE®-UP Registry (The WiSE System Utilization & Performance Registry)

Observe to understand product performance, including patient safety, clinical outcomes, and CRT response information associated with the use of the market-released WiSE System

years of age All Phase N/A
S Stefano Ghio, PI

Registry of Pavia Chronic Heart Failure Patients-observational Study

Registry of Pavia chronic heart failure patients-observational study

18 years of age All Phase N/A
M Manisha Bajpai, PhD

The Salt Study for Heart Failure

The purpose of this study is to understand if low sodium (cardiac) diet is indeed necessary for better health outcomes in patients who suffered heart failure. This study will investigate the association between sodium intake and risk for 30-day re-admission in Heart Failure (HF) patients.

18 years of age All Phase N/A

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