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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,855 clinical trials
L Lucas C Petersen

Medication Withdrawal in Stable HF With Improved LVEF

The goal of this clinical trial is to evaluate the safety and feasibility of withdrawing mineralocorticoid antagonists (MRA) in patients with stable heart failure with improved left ventricular ejection fraction (HFimpEF). The main questions it aims to answer are: Does withdrawal of MRAs lead to a reduction in left ventricular …

18 years of age All Phase 2/3
J Joseph Cheriyan, MBChB MA FRCP FESC FACC

Utilising AI Analysis of Sounds To prEdict heaRt failurE decOmpensation

This is an open-lable, multicenter Phase II study to evaluate the safety, tolerability, and efficacy of IBI363 in advanced melanoma patients

18 years of age All Phase N/A
N Nuria Farre, MD, PhD

Heart Failure Virtual Ward Research Study

The main aim will be to evaluate whether a follow-up with virtual wards reduces HF hospitalisation at three months follow-up. Hospital admission will be defined as any hospital admission, or an emergency room stay of more than 24 h requiring IV diuretics. The secondary objectives will be to evaluate whether …

18 years of age All Phase N/A
E Elaine Franko

Fluid Guided Heart Failure Treatment at the Cleveland Clinic

FIGHT-HF is an exploratory non-randomized open-label study evaluating a heart failure management intervention. The goal of this pilot is to assess the performance of a fluid-guided heart failure management program and Alert Response Guide (ARG) using the Bodyport Cardiac Scale and Congestion Index in 50 adult participants with acute and …

21 years of age All Phase N/A
M Miao

SOCIAL_HF: Improving Social Frailty Through Interactive Learning

The goal of this clinical trial is to learn whether the WeChat-based program "Social Optimization Chat for Interactive Learning for Heart Failure" (SOCIAL\_HF) can improve social frailty in elderly patients with heart failure. The main questions it aims to answer are: Can a 6-week WeChat online group interactive learning program …

60 years of age All Phase N/A
M Markus Wallner, MD

Efficacy of an Assisted Therapy Optimizing Module to Improve Physician Adherence

Heart failure patients within the HM programme

18 years of age All Phase N/A
J John D Munkhaugen, MD, PhD

Management of Patients with Heart Failure At Home After Hospital Discharge

This study aims to assess whether patients with acute heart failure (HF) can achieve the same level of HF-therapies by digital follow-up at home as compared to hospital visits according to the STRONG-HF strategy. Patients admitted to hospital with acute HF will be enrolled and randomized to either follow-up at …

18 - 85 years of age All Phase N/A
M Manuel Wilbring

Aeson TAH System - Post-Market Clinical Follow-up Study

The safety and performance of the Aeson TAH system have been demonstrated for the CE mark approval in December 2020. The purpose of this post-market clinical investigation is to confirm the safety, performance and effectiveness of the Aeson TAH system when used in routine care by surgeons.

18 years of age All Phase N/A
W Whitney Cabral

UPBEAT: Using Polygenic Scores to Guide BB Therapy in HF With Mildly Reduced EF

This study will use polygenic scores, a tool which describes differences in genetics, to examine effectiveness of beta blocker medication in heart failure patients with ejection fraction of 41-50 percent. The study will also assess beta blockers' effect on the changes in left ventricular end-systolic volume index by MRI.

18 - 89 years of age All Phase N/A
D Dr Shirlyn Neo, MBBS, MRCP (UK), MMed, FAMS

Timely Interventions to Enable and Reach Patients With Heart Failure, and Their Caregivers With Palliative Care

There is evidence for the effectiveness and feasibility of the individual components of TIER-HF-PC, however there is a need to test how these individual components interact to allow the researchers to deliver TIER-HF-PC as a model of care in its totality. In the short term, this study will assess if …

21 - 99 years of age All Phase N/A

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