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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,826 clinical trials
A Aayla Jamil, MBBS MPH

Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients

This phase II, multi-center, open-label study will evaluate the safety and efficacy of utilizing HCV-positive donors for heart transplant in HCV-negative recipients treated with sofosbuvir 400 mg / velpatasvir 100 mg (Epclusa®).

18 - 90 years of age All Phase 2
G GUILLAUME BAUDRY

Acute Reno-Cardiac Action of Dapagliflozin In Advanced Heart Failure Patients on Heart Transplant Waiting List

Heart failure affects 1 to 2% of the adult population in developed countries, representing about 55 million people worldwide. Advanced heart failure is a condition where the heart can no longer provide sufficient cardiac output or equilibrate pressures within its chambers, leading to symptoms such as shortness of breath, fatigue, …

18 years of age All Phase N/A
K Kelli Falbo, MSN

A Nurse-Led Weight Monitoring Intervention For Heart Failure Quality of LIfe and Self-Care

Ongoing self-care for heart failure is essential to avoid complications and hospitalization. Supportive strategies are needed; however, patients with heart failure may find many interventions complicated and overwhelming. The purpose of this pilot study is to implement a simple weight tracking tool (Wake and Weigh) to affect self-care and quality …

55 years of age All Phase N/A
D Dr Laurence LC Tan, MBBS, MMed, FAMS

Timely Interventions to Enable and Reach Patients With Heart Failure, and Their Caregivers With Palliative Care

There is evidence for the effectiveness and feasibility of the individual components of TIER-HF-PC, however there is a need to test how these individual components interact to allow the researchers to deliver TIER-HF-PC as a model of care in its totality. In the short term, this study will assess if …

21 - 99 years of age All Phase N/A
S Solomon Gyabaah

30 Days and 90 Days Heart Failure Re-Admission at Komfo Anokye Teaching Hospital

In Ghana, about 88.3 per cent of cardiac admissions are due to Heart failure, making it the leading cause of admission due to heart conditions. Despite improved knowledge on heart failure and an increasing array of evidence-based guideline treatment options, there is still a significant readmission rate worldwide. This may …

18 years of age All Phase N/A
S Saverio Iacopino, MD, PhD

heaRtInsiGHT Alert guIDE: RightAIDE Application of the HeartInsight Acute Heart Failure Predictor in Routine Clinical Practice: Organizational Models and Workflow.

The RightAIDE study is a prospective, multicenter, observational registry designed to evaluate the real-world application of the HeartInsight™ algorithm for predicting acute heart failure (HF) events in patients implanted with a Biotronik ICD or CRT-D device with atrial sensing and Home Monitoring capability. Heart failure is a growing public health …

18 years of age All Phase N/A

Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation

The goal of this clinical trial is to evaluate the effects of a home-based exercise program using mobile technology on physical activity and capacity, frailty and muscle mass, and quality of life in patients with a newly implanted HeartMate 3 left ventricular assist device (HM3 LVAD). Researchers will compare the …

18 years of age All Phase N/A
M Mansoura University Hospital

Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF

This study looks at people with heart failure who are admitted to the hospital. The goal of the study is to understand whether taking a heart failure medicine called angiotensin receptor-neprilysin inhibitor (ARNI) before hospital admission affects short-term health outcomes. The study will compare two groups of participants: those who …

18 years of age All Phase N/A
E Elaine Franko

Fluid Guided Heart Failure Treatment at the Cleveland Clinic

FIGHT-HF is an exploratory non-randomized open-label study evaluating a heart failure management intervention. The goal of this pilot is to assess the performance of a fluid-guided heart failure management program and Alert Response Guide (ARG) using the Bodyport Cardiac Scale and Congestion Index in 50 adult participants with acute and …

21 years of age All Phase N/A
M Mia Levanto

Identifying Markers of Exercise Training in Heart Failure

The heart failure syndrome that occurs when the heart is too sick to properly do its job. One of the main symptoms is difficulty with exercise. One way to improve symptoms is to start patients in a 12 week exercise program called cardiac rehabilitation. Cardiac rehabilitation been shown to improve …

18 - 89 years of age All Phase N/A

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