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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,855 clinical trials
R Rossella Cianci

Genetic and Immunity in Heart Failure

Heart failure is a major health problem with serious consequences on mortality and morbidity worldwide. In chronic heart failure an alteration of the inflammatory state occur. The aim of this study will be to describe the relationship between markers of inflammation in patients with heart failure with preserved ejection fraction, …

18 years of age All Phase N/A

Inspiratory Muscle Training in HFpEF

This study is being done to determine how inspiratory muscle training impacts inspiratory muscle function during exercise in heart failure patients.

18 years of age All Phase N/A
J Joao AC Lima, MD, PhD

Brain Volume and Cardiac Function in Heart Failure

Patients with heart failure (HF) exhibit greater structural brain alterations and higher dementia risks than the general population. Neural atrophy in nearly every region of medical limbic circuit has been observed in HF patients. Reduction of cerebral blood flow has been suggested as the pathophysiological pathway linking HF and structural …

21 years of age All Phase N/A
H Helena Dominguez, MD, PhD

Cardiac Autonomic Dysfunction As a Sign of Irreversible Advanced Heart Failure

The main hypothesis is that autonomic dysfunction cannot improve among patients reaching end-stage heart failure. To evaluate this, patients admitted with acute decompensated heart failure in Bispebjerg hospital, and history one or more admissions with the same condition within the prior year, will undergo repeated brief heart monitoring (10 min). …

18 years of age All Phase N/A
D Diana A Gorog

Safety of AI-Powered Virtual Assistant in Outpatient Management of Heart Failure

The aim of this pilot randomized study is to examine whether integrating the SIRIO-HF virtual assistant (VA) into the outpatient management of participants recently discharged from hospital with a new diagnosis of heart failure (HF), may reduce the need for regular medical assessment and the healthcare burden, reduce variability in …

18 years of age All Phase N/A
B Brian Chan, MD, MPH

Rural Community Peer Partnerships for Improving Methamphetamine-Associated Heart Failure Screening and Engagement

The goal of PEER-Heart is to implement and assess feasibility and preliminary effectiveness of a community peer-facilitated screening for methamphetamine-associated heart failure (MAHF) and linkage to evidence-based cardiology care for people who use methamphetamine in rural areas.

18 years of age All Phase N/A
M Mike Haniff, PhD

iCardia4HF: Multi-component mHealth Intervention for Patients With Heart Failure

The goal of this factorial randomized trial is to examine the independent and synergistic efficacies of two mobile health technology interventions in people with chronic heart failure. The first intervention involves the use of multiple consumer mHealth apps and sensor devices (MyApps) for heart failure self-care (maintenance, monitoring, and management). …

18 years of age All Phase N/A

Mechanisms of Diuretic Resistance in Heart Failure, Aim 3

Randomized double-blind placebo-controlled crossover study design

18 years of age All Phase 1
J Jonathan W Leigh, MPH, MSHI

TEXT4HF: A Randomized Controlled Trial of a Tailored Text Messaging Intervention to Improve Self-Care in Older Adult Patients With Heart Failure

The goal of this study is to determine whether an individually tailored text messaging intervention can improve self-care in older adult patients with heart failure. The main question it aims to answer are: Is a tailored text messaging intervention feasible and acceptable among older adult patients with heart failure? Does …

50 years of age All Phase N/A
S Solomon Gyabaah

30 Days and 90 Days Heart Failure Re-Admission at Komfo Anokye Teaching Hospital

In Ghana, about 88.3 per cent of cardiac admissions are due to Heart failure, making it the leading cause of admission due to heart conditions. Despite improved knowledge on heart failure and an increasing array of evidence-based guideline treatment options, there is still a significant readmission rate worldwide. This may …

18 years of age All Phase N/A

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