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Parkinson's Disease Clinical Trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 628 clinical trials
F Flavia Torlizzi

Serum Biomarkers in Parkinson's Disease at Different Stages

Determine clinical characteristics of parkinsonian patients in various stages of disease; Measure peripheral neurodegeneration, synaptic, and inflammation biomarkers in a population of parkinsonian patients at various stages of disease. Measure vesicular neurodegeneration, synaptic and inflammation biomarkers

18 - 80 years of age All Phase N/A

Online Motor Control in People With Parkinson's Disease

This study aims to better understand how people with Parkinson's control reaching movements. Specifically, we are asking how these individuals respond to different environmental perturbations. Testing includes reaching movements made within a virtual reality set-up.

18 - 85 years of age All Phase N/A
S Sara Penuela, PhD Student

Light Therapy Intervention in Individuals With Parkinson's Disease

The study looks to investigate the effects that light therapy delivered to the frontal cortex could have on Parkinson's disease related symptoms ( both cognitive and motor). The therapy is a non invasive technique that deliverers low level wavelength light to the front part of the head for 12 minutes. …

50 - 80 years of age All Phase N/A
F Francesca Mameli

Genetics in Parkinson's Disease: Behavioral and Cognitive Outcomes

The genetic landscape of Parkinson's disease (PD) is characterised by rare high penetrance pathogenic variants causing familial disease, genetic risk factor variants driving PD risk in a significant minority in PD cases and high frequency, low penetrance variants, which contribute a small increase of the risk of developing sporadic PD. …

18 years of age All Phase N/A

Pathways Mediating Impaired Postural Control in Parkinson's Disease

The purpose of this project is to use transcranial magnetic stimulation (TMS) to explore the state of excitability of corticocortical and corticofugal (cortex to spinal cord, cortex to brainstem to spinal cord) pathways that project to muscles that control the legs and trunk in people with Parkinson's disease. The outcome …

45 - 80 years of age All Phase N/A
R Roberto De Icco, MD

Integrating AI in Postural Rehabilitation for Parkinson's Disease

Postural abnormalities are highly disabling complications of Parkinson's disease (PD). These include camptocormia, anterocollis, and Pisa Syndrome (PS). PS is characterized by a lateral trunk flexion (LTF) typically exceeding 10 degrees, often accompanied by axial rotation, asymmetric shoulder positioning, and poor awareness of the postural alteration. This condition worsens during …

18 years of age All Phase N/A
S Stéphane PRANGE, MD, PhD

Brain Mechanisms of Social Perception in Parkinson's Disease

Social cognition is a complex process that enables humans to interpret social information and behave appropriately in a social environment. Social cognition can be impaired in Parkinson's disease patients, worsening quality of life and relationships with those around them, even at an early stage. These alterations are manifested in particular …

30 - 75 years of age All Phase N/A
H Hao-xuan Lu

7.0T Magnetic Resonance Imaging Study of Parkinson's Disease

This clinical trial study is conducted to detect the imaging characteristics of the patients with Parkinson's diseases (PD) by 7-Tesla (7T) magnetic resonance imaging (MRI).

18 - 80 years of age All Phase N/A
J Jordana Maisel

Speech Learning and Speech Production in Parkinson's Disease

Parkinson's disease, a common movement disorder that results from a breakdown in the brain, often leads to challenges with talking, but less is known about the relationship between difficulties with talking and difficulties with learning to understand speech. By linking these two abilities in individuals with Parkinson's disease using a …

45 years of age All Phase N/A

Gait, Physical Activity, and Sleep in Parkinson's Disease

This study aims to investigate the relationship between balance and gait impairments, physical activity levels, and sleep status in individuals with Parkinson's disease (PD). Both motor and non-motor symptoms of PD significantly affect quality of life, yet these dimensions are often evaluated separately. By examining gait, balance, physical activity, and …

40 - 75 years of age All Phase N/A

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