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Parkinson's Disease Clinical Trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 590 clinical trials
W Wei Bi, PhD

The Study is Being Conducted to Evaluate the Safety and Efficacy of XJN010 Nasal Spray in Patients With Parkinson's Disease Experiencing Off Episodes

The study is being conducted to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of XJN010 Nasal Spray in Patients with Parkinson's Disease Experiencing Off Episodes

30 - 85 years of age All Phase 2
T Tao Feng, PhD

The Safety and Tolerability of XS411CN Injection in Treatment of Primary Parkinson's Disease

This Phase I clinical trial is designed to evaluate the safety, tolerability of a single dose of XS411 (derived dopaminergic neural progenitor cell injection) in patients with primary Parkinson's disease

50 - 75 years of age All Phase 1
H Hanan Khalil Prof Professor, phd

An Online Physical Activity Coaching Intervention for People With PD in Qatar

Regular exercise can improve function and quality of life as well as have other positive behavioral and health-related benefits in people Parkinson's disease (PD). Despite the benefits, insufficient exercise is common among PD individuals, often due to common barriers, emphasizing the importance of empowering individuals with adequate knowledge and self-management …

18 years of age All Phase N/A
A Asiya Uzun, assistant professor

Mental Imagery on Upper Extremity Skills

Parkinson's disease (PD) is the second most common neurodegenerative disease, characterized pathologically by the progressive loss of dopaminergic neurons in the substantia nigra and clinically by the presence of motor symptoms such as bradykinesia, resting tremor, and/or rigidity. Among the motor deficits frequently observed in PD, patients are known to …

40 - 75 years of age All Phase N/A
K Kezhong Zhang

Research on the Brain Mechanism of taVNS in Regulating PD Motor Symptoms

This study is a double blind comparative study exploring the neural underpinnings of taVNS modulating PD motor deficits. We hypothesize that taVNS might improve PD motor deficits by regulating the balance between excitation and inhibition in the primary motor cortex.

40 - 80 years of age All Phase N/A
S Sarah Bedell

Imaging Core Aim 2, and Udall Project 2 Aim 2

More than one million people in the United States have Parkinson's disease (PD) and the prevalence is expected to double by 2040. Over 60% of these individuals will develop debilitating postural instability and gait disturbances (PIGD), including freezing of gait (FOG). With disease progression, axial motor symptoms typically become resistant …

21 years of age All Phase N/A
Y Yannik Rottenberger

Personalized Stimulation Loop for Neurorehabilitation in Parkinson: a Proof-of-principle Study

Parkinson's disease (PD) is a neurodegenerative disease that affects about 1% of the elderly population and accounts for substantial disability and health care costs. Disability is largely driven by mobility deficits caused by impaired gait. Effective treatments are available to restore lower limb function and improve gait, but response to …

18 years of age All Phase N/A

A Phase 2a Multicenter Clinical Trial of TB006 in Participants With Parkinson's Disease

The primary objectives of this study are to assess the efficacy of TB006 in improving motor function and to assess the safety of TB006 in participants with Parkinson's Disease (PD).

50 - 80 years of age All Phase 2
E Ezgi Eryıldız

Telerehabilitation Dual-Task Training for Parkinson's: A Multidimensional Evaluation

In this clinical study, the aim is to assess the effectiveness of telerehabilitation-based dual-task training in improving balance and gait function among individuals diagnosed with Parkinson's Disease. Parkinson's Disease is characterized by motor symptoms such as tremors and slowness of movement, as well as cognitive impairments. While medical treatments help …

30 - 75 years of age All Phase N/A
Y Yang-Pei Chang, M.D.; MSc,

The Clinical Application of Clostridium Butyricum Miyairisan for Motor and Non-motor Symptoms in Parkinson's Disease

This is an open-label, single-center, non-randomized study to assess the efficacy of Clostridium Butyricum Miyairi on the motor and non-motor symptoms of Parkinson's disease

20 - 90 years of age All Phase N/A

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