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Parkinson's Disease Clinical Trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 590 clinical trials

A Study to Assess the Efficacy and Safety of Vutiglabridin in Early Parkinson's Disease Patients

Study Objective To assess the efficacy and safety of vutiglabridin in early Parkindson's disease patients 2. Background Glaceum Inc. has evaluated the safety, tolerability, and pharmacokinetic/pharmacodynamic properties of vutiglabridin in healthy subjects through its Phase 1 trials, and is planning to perform this Phase 2a trial to assess the efficacy …

40 - 75 years of age All Phase 2
T Ties Gaveel

An Integrated and Personalized Lifestyle Approach for People with Parkinson's Disease

The goal of this study is to investigate the effects of a combined lifestyle program on the quality of life in people with Parkinson's Disease. Participants will be randomly assigned to one of two groups, both receiving standard care, a Parkinson Lifestyle Decision aid and an intake meeting with a …

18 years of age All Phase N/A
A Adem Aktürk, PhD

Minimal Clinically Important Difference of the Box and Block Test in Parkinson

The aim of this study is to examine the level of clinical change in gross manual skills of Parkinson's patients who receive conventional physiotherapy. For this purpose, the Box-Block Test will be used, and the amount of change that must occur in the patient's hand functions will be determined for …

50 - 80 years of age All Phase N/A
A Angelina Maric, PhD

Precision Sensorimotor Neurorehabilitation Through Personalized Stimulation Loops

Parkinson's disease (PD) is a neurodegenerative disease that affects about 1% of the elderly population and accounts for substantial disability and health care costs. Disability is largely driven by mobility deficits caused by impaired gait. Effective treatments are available to restore lower limb function and improve gait, but response to …

18 years of age All Phase N/A
f faculty of physical therapy

Effect of Sensory Electrical Stimulation on Resting Tremors in Patients with Parkinson's Disease

Parkinson's disease is one of the most prevalent motor disorders in the world . The disease is progressive and has no known treatment. In addition to a number of psychological and autonomic issues, the disease also cause movement abnormalities which are the most challenging problem because management is still limited …

45 - 60 years of age All Phase N/A
M Merrill R Landers, DPT, PhD

10,000 Step Club: Community Walking Program for People with Parkinson's Disease

The 10,000 Step Club (10KSTC) is a 6-month community walking program for people with Parkinson's disease (PwP) and their caregivers in Las Vegas, Nevada (LV). This program will consist of several weekly, organized walking groups in local parks throughout the LV Valley. Participants in the program will use Nordic walking …

30 - 85 years of age All Phase N/A
J Jui-chi Hsu

The Effect of Exercise Intervention on Posture, Trunk Flexibility and Spine Function in Patients With Parkinson's Disease

The primary goal of this clinical trail is to compare the effect of a five-week specific motor interventions on the postural alignment, trunk range of motion and spine function in patients with Parkinson's disease. The secondary goal is to investigate the effect of specific motor interventions on pain, balance, gait, …

30 - 85 years of age All Phase N/A
A Amy Griffin, DPT

Title: A Multimodal Exercise Program With Gamification for Parkinson Disease (MEP+G)

In this pilot study the research will explore whether exercises and the outcome measures would be acceptable to conduct a more detailed research study. This 8 week pilot study will utilize a comprehensive exercise program that includes non-contact boxing along with computerized games for individuals with Parkinson Disease.

40 - 80 years of age All Phase N/A
M Madison Aasen, MS

Vestibular and Cortical Contributions to Transitions in Freezing of Gait in Parkinson's Disease

Currently, there is a lack of comprehensive knowledge about the role of vestibulospinal drive and cortical activity during self-initiated movement transitions in older adults and people with PD (both with and without FOG). This set of experiments has two primary purposes: to (1) understand the pathological neurophysiology underlying freezing of …

21 - 80 years of age All Phase N/A
Y Ya-Ju Chang, PhD

APA and PAS Training for Gait Initiation in Parkinson's Disease

Our research focused on understanding the interplay between brain excitability and balance function in patients with Parkinson's disease (PD), alongside evaluating effective physical therapy methods. It highlights the prevalence of non-motor disorders and cognitive impairments among PD patients, including balance and postural issues, cognitive function decline, and gait instability. Additionally, …

20 years of age All Phase N/A

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