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Parkinson's Disease Clinical Trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 626 clinical trials
J Jessica N Bentley, MD

Investigating Inhibitory Control Networks in Parkinson's Disease

The purpose of this study is to investigate the brain activity associated with non-motor symptoms of movement disorders, including Parkinson's disease and essential tremor. These movement disorders commonly have significant non-motor features also, including depression, cognitive impairment, decreased attention, and slower processing speeds. The investigators are interested in the brain …

18 years of age All Phase N/A

Exercise for Cognitive Excellence in Parkinson's Disease

This study will evaluate the safety and feasibility of a home-based, virtually-supervised, combined high intensity endurance and resistance training program in people with Parkinson's disease. It will also evaluate the effects of exercise on cognition and underlying exercise-related biological markers (biomarkers).

40 - 80 years of age All Phase N/A
G Georgia Malandraki, PhD

Rehabilitation of Airway Protection in Parkinson's Disease

Airway protective disorders are a prevalent and progressive consequence of Parkinson's Disease (PD), and often result in aspiration pneumonia which is the leading cause of death in PD. Despite this, a large number of patients with PD do not access specialized services to address these critical deficits. The investigators will …

50 - 90 years of age All Phase 2
S Sarah Shaw

Parkinson's Disease and Movement Disorders Clinical Database

The research database contains demographic and family history information, longitudinal information on the clinical symptoms, neuropsychological profile and treatments, stored biological samples, and brain images of patients with Parkinson's disease and related disorders receiving care at the Parkinson's disease and Movement Disorders Center and the Hospital of the University of …

18 years of age All Phase N/A
A Annie Kuan

Targeting Apathy With Music in Parkinson's Disease

Parkinson's Disease (PD) is often accompanied by non-motor symptoms that make treatment more difficult. One such symptom is apathy (lack of motivation and emotion). There are no treatments for apathy in PD, and this remains a major unmet need in PD patients. One possible way to target apathy in PD …

40 - 85 years of age All Phase N/A
L Luke Johnson, PhD

Sleep-specific DBS Therapy in Parkinson's Disease

Sleep-wake disturbances are a major factor associated with reduced quality of life of individuals with Parkinson's disease (PD), a progressive neurological disorder affecting millions of people in the U.S and worldwide. The brain mechanisms underlying these sleep disorders, and the effects of therapeutic interventions such as deep brain stimulation on …

21 years of age All Phase N/A
E Erika Franzén, PhD

Physical Activity in Persons With Parkinson's Disease

Parkinson's disease (PD) is a leading neurodegenerative health condition in Sweden and a public health concern. Although no cure exists, functional independence and participation in society remain top priorities, and can be achieved through targeted physical activity (PA) interventions. To date, few longitudinal cohort studies have been conducted, using PA …

years of age All Phase N/A
H Helen Dawes, PhD

Development of Digital Services for Parkinson's Disease

In this project, ocular motor, pupil and gait data in people with Parkinson's disease (PD) will be collected in order to develop machine learning models for the diagnosis and monitoring of PD. With this, the investigators aim to advance the state of the art in PD diagnosis and monitoring. By …

18 years of age All Phase N/A
D Dulce Maroni, PhD

Attention and Eye Movement in Parkinson's Disease

The goal of this observational and interventional study is to understand how therapeutic deep brain stimulation (DBS) affects attention, perception and cognition in participants with Parkinson's disease (PD) and non-PD movement disorders, including essential tremor (ET) and dystonia (DT). The main questions it aims to answer are: Does impaired control …

19 - 90 years of age All Phase N/A
B Brigette Sosa

Psilocybin Therapy for Depression in Parkinson's Disease

The purpose of this study is to understand whether people with Parkinson's Disease and depression have improvement in their symptoms after psilocybin therapy.

40 - 80 years of age All Phase 2

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