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Ketamine Clinical Trials

A listing of Ketamine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 129 clinical trials
K Kevin Peterson, MD

The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD

This study is aimed to evaluate outpatient ketamine infusion within a military chronic neuropathic pain population and its effect on PTSD. Currently, this is a pilot study with 30 participants. Participants will be randomized to (1) a moderate dose ketamine, (2) moderate dose ketamine +Mg, or (3) a magnesium control …

18 - 70 years of age All Phase 4
R Romain COLLE, MD - PHD

Early Effects of Ketamine vs Placebo With Venlafaxine in Severe Depression Patients

Unipolar major depressive disorder is the leading cause of disability worldwide. The most commonly used treatments for major depressive episodes (MDE) are antidepressant medications. However, they have limited efficacy and their onset of action is long, ranging between 2 to 6 weeks. During this period, hospitalization can become necessary, especially …

18 - 65 years of age All Phase 3
J Juliana zambrano, MD, MPH

A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression

This is a pilot clinical trial to assess the feasibility, safety, and preliminary efficacy of ketamine-assisted group therapy for Spanish-speaking adults with depression

18 - 64 years of age All Phase 1/2
L Lindsay Maguire, MD

Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department

There is currently no readily available pharmacologic intervention for suicidal ideation, a true psychiatric emergency, in the Emergency Department (ED). Investigators aim to trial low-dose, intravenous ketamine, a drug with well-established use in treatment-resistant depression, for patients who present to the ED with suicidal ideation.

18 - 65 years of age All Phase 1
E Evan J. Hernandez Project Manager, MBA

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

The goal of this clinical trial is to learn if ketamine, given during surgery, can help improve recovery for adults with serious orthopedic trauma. The study will test whether ketamine reduces pain, lowers the need for opioids, and improves mental health outcomes like depression and post-traumatic stress disorder (PTSD). The …

18 - 65 years of age All Phase 4
S Sergey Motov, MD

Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED

In situations where intravenous access is not readily available or is unobtainable and the intranasal route is not feasible, another non-invasive route of ketamine administration, such as inhalation via breath-actuated Nebulizer (BAN), is becoming a viable alternative. The BAN allows the controlled, patient-initiated delivery of analgesics in a measured and …

18 - 120 years of age All Phase 4
A Abdelrahim A Sadek, MD, PhD

Ketamine and Levetiracetam as Second-line Antiseizure Medication for Status Epilepticus in Children

About 40% of children with generalized convulsive status epilepticus (GCSE) are not terminated by first-line benzodiazepines (BDZs), and approximately 50% of BDZ-refractory GCSE are not controlled by second-line antiseizure medications. This study investigates the efficacy of ketamine-levetiracetam combination vs. levetiracetam alone for treating children with BDZ-refractory GCSE.

1 - 16 years of age All Phase 2/3

Pre-emptive Analgesia Using Nebulized Ketamine Versus Nebulized Dexmedetomidine in Endoscopic Nasal Surgeries

this study aims to compare the efficacy of pre-emptive nebulized ketamine versus nebulized dexmedetomidine for post operative pain relief in endoscopic nasal surgery

20 - 60 years of age All Phase N/A
H Hasan Mustafić

Nebulized Ketamine for the Treatment of Major Depressive Disorder in an Inpatient Setting

This is a double blind active placebo controlled clinical trial for individuals within an inpatient setting with moderate to severe depression. The purpose of this study is to assess if nebulized ketamine can reduce depressive symptoms.

18 - 88 years of age All Phase 3
A Anesthesia, Pain Management and Surgical ICU Department

Erector Spinae Block Vs Ketamine-based Multimodal Analgesia Protocol in Lumber Decompressive Surgery

The aim of this study is to compare the quality of recovery of the erector spinae plane block (ESPB) versus ketamine-based multimodal analgesia regimen after spine decompressive surgery.

20 years of age All Phase N/A

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