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Ketamine Clinical Trials

A listing of Ketamine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 127 clinical trials
T Tatiana Falcone, M.D.

Ketamine Treatment of Youth Suicide Attempters

Ketamine, an NMDA antagonist, has been shown to have rapid anti- suicidal effects. However, its safety and efficacy and special populations has not been investigated and documented. Several reports in adults suggest rapid decrease of suicidal ideation. In the last decade there is an alarming increase of the number of …

14 - 30 years of age All Phase 3
R Research Coordinator

Ketamine Assisted Psychotherapy for Opioid Use Disorder

This pilot clinical trial aims to assess the preliminary efficacy of ketamine as an adjunct for a mindfulness-based intervention for opioid use disorder.

18 years of age All Phase 1/2
J John Farley

Ketamine-Assisted Recovery for Methamphetamine Use Disorder & HIV

The goal of this clinical trial is to learn whether it is possible to use intramuscular (IM) ketamine in combination with psychotherapy to treat moderate-to-severe methamphetamine use disorder (MeUD) in publicly insured patients with or at-risk for HIV disease. The main questions it aims to answer are: Do publicly insured …

18 - 69 years of age All Phase 2

Efficacy of Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation

This study aims to compare efficacy of sedation between Dexmedetomidine-Propofol and Ketamine-Propofol combinations in the upper or lower gastrointestinal system endoscopy. We compare between 2 combinations as regard hemodynamic stability, post operative side effects as occurrence of delirium, nausea, vomiting, headache, hallucination or agitation.

18 - 60 years of age All Phase N/A
R Robert DeLorenzo, MD

Ketamine & Crisis Response Plan for Suicidal Ideation in the ED

The goal of this randomized pilot trial is to assess the feasibility of administering a combination of 100mg intramuscular (IM) ketamine and Crisis Response Plan (a short psychosocial intervention) for patients with acute suicidality in the context of the Emergency Department setting. This study will assess a combination of a …

18 - 70 years of age All Phase 2/3
N Nicolas Lejeune, PhD

Ketamine to Treat Patients With Post-comatose Disorders of Consciousness

The investigators will run a Randomized Clinical Trial with 30 patients with disorders of consciousness (DoC), with intravenous subanesthetic doses of ketamine. Patients will simultaneously undergo TMS-EEG. The piloting will be done on 3 patients, with EEG only.

18 - 65 years of age All Phase 2/3
T Trent Reed, DO

Ketamine as a Supplement to Local Anesthesia for Minor Procedures

This trial is a double-blind randomized controlled clinical trial of adults and children (ages 7 to less than 70 years). Patients who present to the ED and who undergo minor bedside procedures that require local anesthesia will be divided into two groups: The first group will be treated with 0.7 …

7 - 70 years of age All Phase 4
Z Zamri Zuhdi, MD

Evaluation of Ketamine as Sedative Agent in Endoscopic Retrograde Cholangiopancreatography (ERCP)

This is a study evaluating the usage of Ketamine as sedative agent in ERCP. The usage of Ketamine will be compared to the standard sedation in our center, which is Midazolam in combination with Pethidine as analgesia.

16 years of age All Phase 4
J Jamal Kara, BSc MSc

Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches

Chronic daily headaches (CDH) poses a significant burden on patients, healthcare systems and the society. Intravenous (IV) ketamine infusion, an intervention that is widely available and scalable, can treat CDH by reversing receptor-mediated sensitization. This study is a multicenter, placebo-controlled, parallel group randomized trial with blinding of participants and observers …

18 years of age All Phase 3
j joaquim vieira, MD

Ketamine Versus Magnesium Sulfate in the Time and Awakening Quality of General Anesthesia.

The introduction of the laparoscopic technique for cholecystectomy significantly reduced the incidence and intensity of postoperative pain, with improvement in other markers, such as patient satisfaction, and reduction in hospital stay. However, pain in the postoperative period of laparoscopic cholecystectomy is still a concern that challenges modern anesthesiology. Ketamine and …

18 - 70 years of age All Phase N/A

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