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Ketamine Clinical Trials

A listing of Ketamine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 118 clinical trials
O Omar Soliman

Low Dose Dexmedetomidine Versus Ketamine in Multiple Fracture Ribs

In our study, we assess the diaphragmatic function, pain quality and anti-inflammatory properties between low dose infusion of dexmedetomidine and ketamine in patients with multiple fracture ribs on conservative treatment.

18 - 65 years of age All Phase 3
I Ilan Harpaz-Rotem, PhD

Enhancing Week-long Psychological Treatment for PTSD With Ketamine

The purpose of this study is to test if the combination of ketamine, vs midazolam, with an intensive trauma-focused psychotherapy will be more effective in relieving post-traumatic stress disorder (PTSD). This week-long treatment has the potential to produce a significant therapeutic effect that otherwise would take months to occur. The …

21 - 70 years of age All Phase 2
B BEN ALI MECHAAL

Comparison of Intravenous Lidocaine vs Ketamine in Colorectal Surgery

Patients undergoing open colorectal surgery were randomly divided into two groups: Intravenous Lidocaine (IV-Lido) vs Intravenous Ketamine (IV-Keta). For the IV-Lido group, patients received a loading dose of Lidocaine than a continuous infusion over twenty-four hours. For the IV-Keta goup, patients received a loading dose of Ketamine than a continuous …

18 - 90 years of age All Phase N/A

Ketamine for Preventing Post-Spinal Hypotension in Orthopedic Surgery

This randomized, double-blind, controlled clinical trial investigates the efficacy of a sub-anesthetic dose of ketamine (0.5 mg/kg IV) in preventing post-spinal hypotension in patients undergoing elective orthopedic surgeries under spinal anesthesia. The study compares ketamine with placebo (normal saline) in terms of blood pressure stability and incidence of hypotensive episodes …

18 years of age All Phase N/A
L LHMC Department of Anesthesiology

Reducing Pain With Methadone and Ketamine in Liver Transplant

The goal of this clinical trial is to learn if using methadone and ketamine during an adult deceased donor liver transplant can help decrease pain after surgery. The main questions it aims to answer are: What impact does using methadone and ketamine during a deceased donor liver transplant have on …

18 years of age All Phase 4
E Emad M. Abdelhafez, Lecturer

Comparison of the Hemodynamic Effects of Ketamine - Dexmedetomidine (Ketodex) Versus Propofol-ketamine Admixture (Ketofol) During Induction of Anesthesia in Elderly: A Randomized Comparative Study

To compare the hemodynamic effects of Ketamine-Dexmedetomidine admixture (Ketodex) versus propofol-ketamine admixture (Ketofol) during induction of anesthesia in elderly

65 years of age All Phase N/A

Ketamine in OCD: Efficacy and Effects on Stress and Cognition

The main goal of this trial is to demonstrate therapeutic efficacy of low dose ketamine in patients with OCD. We expect that ketamine will alleviate symptoms in the hours following application, but also - if effective - that the anti-OCD effects might last for several days after a single infusion.

18 years of age All Phase N/A
M Marcus Herdener, PD Dr. med.

Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction

The goal of this clinical trial is to learn about the effects of the combination of ketamine and realtime functional magnetic resonance imaging (fMRI) neurofeedback training in individuals with cocaine use disorder. The main questions the investigators aim to answer are Can the investigators observe a positive, significant effect on …

18 - 55 years of age All Phase 2

Comparison of Dexmedetomidine + Ketamine for Postoperative Pain in C-Section

This study aims to compare three different doses of dexmedetomidine, when combined with a fixed dose of ketamine, for pain control in women undergoing cesarean section. The goal is to find the most effective combination with the fewest side effects.

18 - 50 years of age Female Phase 4
M Mark A Ware, MD

Music as an Adjunct to Ketamine Therapy for Chronic Pain

Intravenous (IV) ketamine is a treatment option for patients with chronic pain that does not respond to standard therapies, primarily working by blocking NMDA receptors in the brain. Beyond pain relief, ketamine can produce dissociative sensations, classifying it as an atypical psychedelic or mind-altering drug, and may enable patients to …

18 years of age All Phase N/A

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