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a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

Found 11,315 clinical trials
J Jane Kelly

A Study to Find a Suitable Dose of Exl-111 for Further Research

This is a Phase 1, randomized, double-blind, placebo-controlled, single and multiple ascending dose trial of Exl-111 in healthy participants. The trials consists of 2 parts, as follows: Part A (SAD): Up to 5 dose cohorts, each with 8 participants, randomized into 2 arms: Exl-111 and placebo. Part B (MAD): Up …

18 - 55 years of age All Phase 1
L Lauren Crowe, BS

A Comparison Of Primary TKA Rehabilitation Using A Smart Orthotic Versus Outpatient Physical Therapy

This will be a prospective, randomized, noninferiority clinical trial comparing rehabilitation methods post-total knee arthroplasty (TKA). Population of interest is adult hip/knee clinic patients over age 18 who are indicated for unilateral primary total knee arthroplasty. All TKA patients are prescribed physical therapy (PT) for rehabilitation post-operatively. The investigators will …

18 - 100 years of age All Phase N/A
M Marleigh Treger, BS

A Pilot of a Personalized Circadian mHealth to Improve Sleep in Night Shift Workers

The goal of this project is to establish the evidence base for equitable accessibility and implementation of the precision sleep medicine mobile application, SHIFT.

18 years of age All Phase N/A
E Eric JOUVENT, PhD

Constitution of a Clinico-radiological Database and a Biobank for Patients With Lacunar Infarcts

The aim of this study is to determine in patients with a recent lacunar strokes (\<15 days), the natural history of cognitive disturbances and disability.

18 years of age All Phase N/A

A Novel Two-Tooth Clip for ESD and EFTR of GIST: A Prospective RCT

This study is designed to evaluate the efficacy and safety of a novel two-tooth endoscopic clip, utilized in a "clip with line" traction configuration, during endoscopic resection procedures (ESD and EFTR) of GIST. The novel clip's dual-tooth design is intended to provide a more secure anchor on the lesion, enabling …

18 - 85 years of age All Phase N/A
A Amy West, RN

A Prospective Study of a Lifestyle Medicine Survivorship Program for Patients With Gynecologic Cancer

This study will examine the effects of an 8-week intervention called the Healthy Eating Active Lifestyle (HEAL)-GYN program on participants' 1) self-efficacy 2) lifestyle factors, including physical activity and diet, as well as mental health and overall well-being, and 3) biometrics and biomarkers.

18 years of age Female Phase N/A

A Clinical Study of AK0610

The study consists of two parts: dose escalation and expansion. It includes five cohorts in the dose-escalation phase and two expansion cohorts based on pharmacokinetic data.

18 - 50 years of age All Phase 1
M Marjolaine WILLEMS, PH

Multidisciplinary Evaluation and a Genome-wide Analysis in a Cohort of Idiopathic Short Stature Patients

This trial aims to evaluate the prevalence of idiopathic short stature among children whose growth is above -2,5SD (AFPA- CRESS/Inserm -CompuGroup Medical 2018 curve) or above -2SD of the parental target size (taking child gender into account), after exclusion of classical pediatric and endocrinologic pathologies, and to evaluate the prevalence …

4 - 18 years of age All Phase N/A
M Mathilde Doyard

A Natural History Study in Children With a Type II Collagen Disorder With Short Stature

There are relatively few data available on type II collagen disorders, and evidence is lacking on the disease course in relation to symptoms and development of complications, the level of actual disease burden over time as well as data to support identification of possible risk factors. This study aims to …

- 12 years of age All Phase N/A
R Raffaella Dobrina, RN, BSN, MSN

Effectiveness of a mHealth Application as a Family Supportive Tool in Pediatric Otolaryngology Perioperative Process

Tonsillectomy and/or adenoidectomy are common surgeries in children. Authors report how distressed children and their families are by perioperative processes. Fear of the unknown can put a strain on the preoperative period, while pain and other possible complications such as fever, vomiting, restricted oral feeding or bleeding can create difficulties …

2 - 10 years of age All Phase N/A

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