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a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

Found 11,120 clinical trials
C Chloé Melchior, MD, PhD, PI

Effectiveness of a Dietary Supplement in Irritable Bowel Syndrome

Irritable bowel syndrome (IBS) affects around 5% of the general population and remains a daily problem in clinicians' practices, with inconsistent efficacy of treatments despite patients' high expectations. Intestinal hyperpermeability and visceral hypersensitivity are the two major components of IBS, and both can disrupt gastrointestinal function and ultimately impair patients' …

18 - 75 years of age All Phase 2
H Hesham Rashid, Professor

Intra-Articular Dexmedetomidine: A Treatment for Chronic Knee Pain

Chronic knee osteoarthritis (KOA) is a painful condition with limited treatment options. Non-pharmacological approaches often fall short, leading to decreased quality of life. Ozone therapy, a simple and affordable treatment, has shown promise for pain relief. Dexmedetomidine (DEX), a sedative and analgesic, has been used successfully as an adjuvant to …

40 - 75 years of age All Phase N/A
J Jocelyn Hernandez, LSW

Optimizing a Bio-behavioral Intervention for Sustained Viral Suppression

The study will test two behavioral intervention components to identify the combination of the two components that best supports people who inject drugs to achieve and sustain HIV viral load suppression. The study design is a 2-to-the-2 factorial experiment. The 2 represents the level of each component: 0 (receive) or …

18 years of age All Phase N/A
L Lin Feng

A Study of CC312 for Relapsed/Refractory Autoimmune Diseases

This study is an open-label, multiple ascending dose investigator-initiated trial (IIT) designed to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of CC312 in adult patients with relapsed or refractory autoimmune diseases.

18 - 65 years of age All Phase N/A
D Dongyang Liu

A Clinical Study of GenSci134 in Healthy Male Adults

To check how safe and well-tolerated a single subcutaneous injection of GenSc134 is in healthy male volunteers

18 - 45 years of age All Phase 1
H Hongkun Cai

A Study of AL58805 in Patients With Advanced Tumors

This Phase I clinical trial is a dose-escalation, multicenter study in patients with advanced solid tumors. It includes tolerance studies of sequential multiple oral doses of AL58805 and pharmacokinetic studies of single and multiple doses, analyzing the tolerance range of multiple doses, observing the maximum tolerated dose (MTD) and dose-limiting …

18 years of age All Phase 1
M Maria D Lopez, MBA

A Polymer Film Device to Treat Excessive Palmar Sweating

Perspiration or sweating is a normal physiological response to increased body temperature, environmental heat and humidity, emotions, nervousness, or physical exertion. Perspiration occurs when sweat is secreted from sweat glands, travels through sweat ducts and exits sweat pores to coat the skin's surface. The evaporation of sweat from the skin …

18 years of age All Phase N/A
L Laure Patrier, PhD

Intradialytic Exercise and Remote Ischaemic Preconditioning: a Cardioprotective Role ?

The aim of this clinical trial is to evaluate whether intermittent exercise and remote ischaemic preconditioning (rIPC) during haemodialysis (HD) can provide cardioprotection in adult patients (aged 20-79 years) undergoing HD for at least 3 months. The main questions to be answered are Does intermittent exercise or rIPC reduce myocardial …

20 - 79 years of age All Phase N/A

A Trial of SHR-4849 in Advanced Solid Tumors

The study is being conducted to evaluate the safety, tolerability and efficacy of SHR-4849 injection in Advanced Solid Tumors. To explore the reasonable dosage of SHR-4849 for Advanced Solid Tumors.

18 - 75 years of age All Phase 1
C Christian J Hopfer, MD

A Study of Cannabidiol in Young Adult Cannabis Users

The investigators will study the harm-reducing effect of hemp-derived CBD in non-treatment-seeking emerging adults who use cannabis regularly. The study will use a novel naturalistic cannabis administration approach, which examines ecologically valid cannabis use utilizing a mobile lab setting to assess the effects of the cannabis products the participants regularly …

18 - 25 years of age All Phase 2

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