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a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

Found 10,668 clinical trials

A Study of JNJ-87890387 for Advanced Solid Tumors

The purpose of this study is to determine recommended phase 2 dose(s) (RP2Ds) of JNJ-87890387 and to determine the safety of JNJ-87890387 at the RP2D(s).

18 years of age All Phase 1
M Marissa Podell

A PiLot ClinicaL TrIal of ParicAlcitol for ChroNiC PancrEatitis

The purpose of this pilot study to examine the feasibility and acceptability of paricalcitol in adults with Chronic Pancreatitis (CP).

18 - 75 years of age All Phase N/A
E Emmanuelle DERNIS, MD

Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis

In rheumatoid arthritis (RA), the consensual 1st line conventional synthetic disease modifying antirheumatic drugs (csDMARD) of RA is methotrexate (MTX). In case of contra-indication or intolerance to MTX, leflunomide is an alternative. If the treatment target is not achieved with csDMARD strategy, addition of a biological DMARD (TNF inhibitors, anti-Interleukin …

18 years of age All Phase 3
D David Horton, MS

Adjunctive Effects of Psilocybin and a Formulation of Buprenorphine

Primary Aim: In participants with OUD, to characterize adverse events associated with adding two psilocybin doses to a stable buprenorphine-naloxone formulation. Secondary Aim: To evaluate the effect of psilocybin treatment on the effectiveness of a buprenorphine-naloxone maintenance therapy. Secondary Aim: To evaluate the effect of concurrent buprenorphine-naloxone use on the …

21 - 65 years of age All Phase 1

Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones

This study tests whether hydroxycitrate, a molecule closely related to citrate, can reduce calcium phosphate stone recurrence.

21 - 99 years of age All Phase 4
D Delphine Oudiette, PhD

Toward a Real-time Access to Sleepers' Mental Content

Sleep is crucial for global cognitive functioning, but its exact functions and mechanisms are still poorly understood. Cognitive studies of sleep typically rely on linking electrophysiological changes measured during sleep with behavioral and neural changes collected in tasks performed during wakefulness. What concomitantly happens in the mind of sleeping subjects …

18 - 35 years of age All Phase N/A

A Study of EBC-129 in Advanced Solid Tumours

This study will assess the safety and tolerability of EBC-129 as a single agent and in combination with pembrolizumab in patients with advanced solid tumours

18 years of age All Phase 1

A Study for HSK39775 in Participants With Solid Tumors

This research is designed to determine if HSK39775 is safe, tolerable, and has anti-cancer activity in patients with advanced solid tumors.

18 years of age All Phase 1/2
A Andriana C Kaliora, Ass. Prof

Bioavailability and Satiety Study of a Cretan Carob Beverage

This is an interventional, open-label, single-group, bioavailability and satiety postprandial crossover study. The aim of the study is to evaluate the bioavailability of active compounds of a beverage prepared with Cretan carob powder, as well as the subjective and objective satiety in healthy individuals after its consumption.

18 years of age All Phase N/A
O Olof Molander

Internet-CBT for Gambling Disorder - a Randomized Controlled Trial

The study is a randomized controlled trial (Total N=150; each condition n=75) of internet-based cognitive behavioral therapy (iCBT), with measures at pre, weekly during treatment, post, three and at six month follow-up. Participants will be assigned to either standard iCBT and "Spelpaus" (treatment condition), or "Spelpaus" only (control condition).

18 years of age All Phase N/A

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