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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,619 clinical trials
I Ilias Houda, MD

Chemoradiotherapy With Surgery Followed by Consolidation Durvalumab

Lung cancer presents a significant treatment challenge, particularly in the heterogeneous stage III NSCLC patient population. While chemotherapy combined with high-dose radiotherapy (60 Gy in 30 fractions of 2 Gy once daily) is currently the recommended approach for unresectable stage III cases, it is associated with significant rates of locoregional …

18 years of age All Phase 4

Sphenopalatine Ganglion Block in Bimaxillary Orthognathic Surgery

The goal of this clinical trial is to evaluate whether sphenopalatine ganglion (SPG) block helps with intraoperative pain control, reduces postoperative edema, and decreases pain in adults aged 18 to 45 undergoing bimaxillary orthognathic surgery. The main questions it aims to answer are: Does SPG block help decrease postoperative swelling …

18 - 45 years of age All Phase N/A
D Director of Research

Knee Flexionater to Avoid Motion Restoring Surgery

The goal of this clinical trial is to learn whether adding a stretching device to standard physical therapy can help people regain knee bending after total knee replacement surgery. Some people have difficulty bending their knee during recovery. When this happens, doctors may recommend another procedure called motion-restoring surgery to …

40 years of age All Phase N/A

Rhizarthrosis Surgery and Functional Recovery: Arthroplasty vs. Trapezectomy

Rhizarthrosis is a form of osteoarthritis that affects the trapeziometacarpal joint at the base of the thumb, which is more common in women over 50. Genetic and hormonal factors as well as the frequency of certain physical movements may contribute to its appearance. Surgical treatment is recommended if medical treatment …

45 - 85 years of age All Phase N/A
L Lilliam Flores, PhD

Eating Behavior and Weight Trajectory After Bariatric Surgery

Studying the mechanisms of weight regain (WR) may provide much needed insight into sustained obesity management. The aim of this five-year, prospective, multicenter study is to evaluate the association among eating patterns (specifically maladaptive behaviors), certain psychological variables and weight trajectory in the short- and long-term after bariatric surgery (BS). …

18 - 70 years of age All Phase N/A
C Charlotte Dandurand

Anterior vs Posterior Surgery for Lumbar Isthmic Spondylolisthesis

Currently there is no consensus on the best surgical treatment of patients with symptomatic isthmic spondylolisthesis (IS). Clinical equipoise exists amongst experienced clinicians on the various surgical techniques available. This study will involve multiple phases to answer specific research questions comparing anterior and posterior interbody fusion in patients with lumbar …

18 years of age All Phase N/A
M Maxime Antony, MD

Unexpected Positive Cultures in Rotator Cuff Revision Surgery

In the context of rotator cuff re-intervention, the impact of Unexpected Positive Cultures (UPC) is not documented, and their management has not been studied, particularly regarding indications for antibiotic therapy, which is currently not a consensus. A prospective interventional study will be implemented to compare the results of non-randomized patient …

18 years of age All Phase N/A
D Daniel Mansour, MD

Post-operative Urinary Retention (POUR) Following Thoracic Surgery

Inability to urinate a common complication that happens to many patients after a surgery, especially in men over 60 years of age who undergo surgery on their chest. Urinary retention is uncomfortable, increases anxiety, increases hospital length of stay, and leads to more procedures such as putting in a bladder …

50 years of age Male Phase 1/2
J Jakub Szrama, PhD

The Hypotension Prediction Index in Major Abdominal Surgery

The goal of this randomized clinical trial is to compare different types of advanced hemodynamic monitoring in patients undergoing major abdominal surgery. Participants undergoing major abdominal surgery will receive anesthesia with two different types of hemodynamic monitoring - group A will receive arterial pressure cardiac output algorithm with the FloTrac …

18 - 80 years of age All Phase N/A
C Catherine Roth, MPH

Digital Literacy in Caregivers of Pediatric Surgery Patients

The purpose of this study is to describe the digital literacy of caregivers of pediatric surgical patients. The investigators hypothesize that caregivers of minority race, language of care other than English, and low neighborhood opportunity will have lower prevalence of digital literacy.

- 18 years of age All Phase N/A

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