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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,619 clinical trials
E Emma Starr, BHSc

No Surgery Trial / Two Dose-escalation Strategies

A randomized study of 131 patients. Patients with a clinical T2-3 N0 rectal cancer will be randomized to two arms (arm A: standard chemoradiation (45 Gy in 25 with concomitant 5-FU or Xeloda chemotherapy) and an external beam boost of 9 Gy compared to arm B: standard chemoradiation (45 Gy …

18 - 80 years of age All Phase 2/3
J Jeremy Reeves, BS

Sternotomy PIFB Block in Open Heart Surgery

The purpose of this study is to evaluate if the use of a bilateral nerve block with a local anesthetic (ropivacaine), as part of a standard of care pain control regimen (called multimodal analgesia \[MMA\]), has a favorable effect on our institutional MMA pain regimen. Subjects will go through the …

18 years of age All Phase N/A
K Kaitlyn Lillemoe

Hospital for Special Surgery Shoulder Arthroplasty Cohort

Total joint replacements are some of the most successful medical devices developed over the last fifty years. They enable millions of people to remain ambulatory and pain free, with minimal risk. In 2002, over 200,000 total hip replacements, 350,000 total knee replacements, and 25,000 total or partial shoulder replacements were …

18 years of age All Phase N/A
A Anastasia Whitson, BS

Optimizing Infection Prophylaxis Prior to Shoulder Surgery

The goal of this interventional study is to determine the amount of skin C. acnes reduction with increased pressure during the chlorhexidine gluconate, brand name ChloraPrep, application. The main question it aims to answer is: Does changing the pressure applied during the ChloraPrep application impact the amount of C. acnes …

18 - 89 years of age Male Phase N/A
X Xiaoying Li, M.D.

Radical Radiotherapy Versus Radical Surgery for UTUC

This study is a prospective cohort study, and the proposed plan is to recruit 30 patients with radical radiotherapy for renal pelvic ureteral cancer, according to the actual clinical situation, enrolling the same period of time to choose the operation of the elderly, combined with the risk of anaesthesia or …

18 - 80 years of age All Phase N/A
K Kristie Geisler, BS

ES Catheter vs Cryoablation After Pectus Surgery

Participants will be randomized to receive ES catheter or cryoablation for pain management after the Nuss procedure. The goal of this study is to compare the following between the two groups: Time to achieve short-term physical therapy goals and long-term functional outcomes Compare immediate and long-term postoperative opioid use Compare …

12 - 21 years of age All Phase N/A
C Carolin Tran

Reboxetine for Sleep Apnoea After ENT Surgery

This pilot study will establish the feasibility of a larger trial to investigate whether reboxetine, a medication used to treat depression, can reduce the severity of obstructive sleep apnea (OSA) including increased blood oxygenation in post-surgical OSA patients where positive airway pressure (CPAP) therapy is either frequently poorly tolerated or …

18 years of age All Phase 2
R Rachel H Park, MD

Effect of Nitropaste in Chest Masculinizing Surgery

Nitropaste is a topical agent that contains 2% nitroglycerin. It is an effective vascular smooth dilator, with more powerful effect on venous vasculature than arterial vasculature. While its main indication is for angina pectoris, there have been many studies showing improved survival of axial and random pattern flaps. Furthermore, recent …

18 years of age Female Phase 4
V Vladimir Nekhendzy, MD

Transcranial Electrostimulation and Obstructive Sleep Apnea Surgery

Postoperative pain after major surgery for obstructive sleep apnea (OSA), such as palatopharyngoplasty (PPP) and maxillomandibular advancement (MMA) is moderate-to-severe, and may persist for weeks. Control of this pain may be difficult, because OSA patients are very sensitive to traditional opioid pain medications, and their side effects. Poorly controlled pain …

18 - 70 years of age All Phase N/A

Standardized Sleep Bundle for Cardiac Surgery Patients

The goal of this clinical trial is to evaluate the feasibility of using a standardized sleep bundle in adults undergoing cardiac surgery. The main questions it aims to answer are: Can eligible participants be recruited and retained in the study? Can participants follow the study procedures, including using sleep aids …

19 years of age All Phase N/A

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