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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,669 clinical trials
C Carolin Tran

Reboxetine for Sleep Apnoea After ENT Surgery

This pilot study will establish the feasibility of a larger trial to investigate whether reboxetine, a medication used to treat depression, can reduce the severity of obstructive sleep apnea (OSA) including increased blood oxygenation in post-surgical OSA patients where positive airway pressure (CPAP) therapy is either frequently poorly tolerated or …

18 years of age All Phase 2
R Rachel H Park, MD

Effect of Nitropaste in Chest Masculinizing Surgery

Nitropaste is a topical agent that contains 2% nitroglycerin. It is an effective vascular smooth dilator, with more powerful effect on venous vasculature than arterial vasculature. While its main indication is for angina pectoris, there have been many studies showing improved survival of axial and random pattern flaps. Furthermore, recent …

18 years of age Female Phase 4

Standardized Sleep Bundle for Cardiac Surgery Patients

The goal of this clinical trial is to evaluate the feasibility of using a standardized sleep bundle in adults undergoing cardiac surgery. The main questions it aims to answer are: Can eligible participants be recruited and retained in the study? Can participants follow the study procedures, including using sleep aids …

19 years of age All Phase N/A
I Ilias Houda, MD

Chemoradiotherapy With Surgery Followed by Consolidation Durvalumab

Lung cancer presents a significant treatment challenge, particularly in the heterogeneous stage III NSCLC patient population. While chemotherapy combined with high-dose radiotherapy (60 Gy in 30 fractions of 2 Gy once daily) is currently the recommended approach for unresectable stage III cases, it is associated with significant rates of locoregional …

18 years of age All Phase 4

Sphenopalatine Ganglion Block in Bimaxillary Orthognathic Surgery

The goal of this clinical trial is to evaluate whether sphenopalatine ganglion (SPG) block helps with intraoperative pain control, reduces postoperative edema, and decreases pain in adults aged 18 to 45 undergoing bimaxillary orthognathic surgery. The main questions it aims to answer are: Does SPG block help decrease postoperative swelling …

18 - 45 years of age All Phase N/A
D Director of Research

Knee Flexionater to Avoid Motion Restoring Surgery

The goal of this clinical trial is to learn whether adding a stretching device to standard physical therapy can help people regain knee bending after total knee replacement surgery. Some people have difficulty bending their knee during recovery. When this happens, doctors may recommend another procedure called motion-restoring surgery to …

40 years of age All Phase N/A
M Malgorzata Reysner, M.D. Ph.D.

Tranexamic Acid in Pediatric Idiopathic Scoliosis Surgery

This study will evaluate whether tranexamic acid (TXA), a medication used to reduce bleeding, is effective and safe in children undergoing surgery for idiopathic scoliosis. Significant blood loss is common during this type of surgery and often requires blood transfusions. Participants will be randomly assigned to one of three groups: …

10 - 18 years of age All Phase N/A
A Alberte Lund, MD

Unilateral vs. Bilateral Lung Volume Reduction Surgery

This study compares two surgical approaches for patients with severe Chronic Obstructive Pulmonary Disease (COPD) and severe emphysema: unilateral (operating on one lung) versus bilateral (operating on both lungs) lung volume reduction surgery (LVRS).

18 - 75 years of age All Phase N/A

Rhizarthrosis Surgery and Functional Recovery: Arthroplasty vs. Trapezectomy

Rhizarthrosis is a form of osteoarthritis that affects the trapeziometacarpal joint at the base of the thumb, which is more common in women over 50. Genetic and hormonal factors as well as the frequency of certain physical movements may contribute to its appearance. Surgical treatment is recommended if medical treatment …

45 - 85 years of age All Phase N/A
L Lilliam Flores, PhD

Eating Behavior and Weight Trajectory After Bariatric Surgery

Studying the mechanisms of weight regain (WR) may provide much needed insight into sustained obesity management. The aim of this five-year, prospective, multicenter study is to evaluate the association among eating patterns (specifically maladaptive behaviors), certain psychological variables and weight trajectory in the short- and long-term after bariatric surgery (BS). …

18 - 70 years of age All Phase N/A

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