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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,632 clinical trials
P Peter Wijkstra, Prof

Diaphragm Paralysis: Surgery or Mechanical Ventialion

Summary Rationale: The diaphragm is a dome-shaped muscle which separates the thoracic cavity from the abdomen. In patients with diaphragm paralysis the treatment (surgery versus non-invasive ventilation) is based on physician preference, not sound scientific evidence. Clearly studies are needed to guide a scientific decision making. Objective: In this pilot …

18 years of age All Phase N/A
G Giampaolo Perri, Medical Doctor

Surgery for Locally Unresectable Pancreatic Cancer

Pancreatic cancer is a severe disease often diagnosed at an advanced stage, when surgery is not possible. New chemotherapy treatments can sometimes shrink the tumor and make surgery an option. This study aims to understand if surgery after such treatments can improve survival and quality of life in selected patients …

18 years of age All Phase N/A
A Andrea Russo

A PREDICTIVE ALGORITHM IN AORTIC SURGERY

We will enroll patients scheduled for abdominal aortic aneurysm repair and divide in two groups; in the control group the hemodynamic optimization will be made based on standard cardiovascular parameters showed in the Hemosphere platform. In the interventional group the hemodynamic optimization will be made based on the hypotension prediction …

18 years of age All Phase N/A
M Mohamed Diaa Zain El Abedeen, Professor

Facial Conformation Meshes for Orthognathic Surgery

This study is a retrospective analysis that evaluates the accuracy of 3D soft tissue simulation in bimaxillary orthognathic surgery for Class III dentofacial deformities. The study integrates segmented 3D facial conformation meshes and regional aesthetic subunits to enhance soft tissue prediction accuracy. Key Aspects of the Study: Study Design: Retrospective …

18 - 50 years of age All Phase N/A
K Kaitlyn Lillemoe

Hospital for Special Surgery Shoulder Arthroplasty Cohort

Total joint replacements are some of the most successful medical devices developed over the last fifty years. They enable millions of people to remain ambulatory and pain free, with minimal risk. In 2002, over 200,000 total hip replacements, 350,000 total knee replacements, and 25,000 total or partial shoulder replacements were …

18 years of age All Phase N/A
J Juha KA Rinne, MD

Day Case Colectomy: Optimizing Short Stay-surgery.

HRV measurement of patients recovering from laparoscopic colorectal resection for any pathology.

18 - 100 years of age All Phase N/A
J Jeremy Reeves, BS

Sternotomy PIFB Block in Open Heart Surgery

The purpose of this study is to evaluate if the use of a bilateral nerve block with a local anesthetic (ropivacaine), as part of a standard of care pain control regimen (called multimodal analgesia \[MMA\]), has a favorable effect on our institutional MMA pain regimen. Subjects will go through the …

18 years of age All Phase N/A

Sphenopalatine Ganglion Block in Bimaxillary Orthognathic Surgery

The goal of this clinical trial is to evaluate whether sphenopalatine ganglion (SPG) block helps with intraoperative pain control, reduces postoperative edema, and decreases pain in adults aged 18 to 45 undergoing bimaxillary orthognathic surgery. The main questions it aims to answer are: Does SPG block help decrease postoperative swelling …

18 - 45 years of age All Phase N/A
E Emma Starr, BHSc

No Surgery Trial / Two Dose-escalation Strategies

A randomized study of 131 patients. Patients with a clinical T2-3 N0 rectal cancer will be randomized to two arms (arm A: standard chemoradiation (45 Gy in 25 with concomitant 5-FU or Xeloda chemotherapy) and an external beam boost of 9 Gy compared to arm B: standard chemoradiation (45 Gy …

18 - 80 years of age All Phase 2/3
C Charlotte Walter, MD

ES Catheter vs Cryoablation After Pectus Surgery

Participants will be randomized to receive ES catheter or cryoablation for pain management after the Nuss procedure. The goal of this study is to compare the following between the two groups: Time to achieve short-term physical therapy goals and long-term functional outcomes Compare immediate and long-term postoperative opioid use Compare …

12 - 21 years of age All Phase N/A

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