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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,670 clinical trials
W Wilton vanKlei, MD

Long Term Cardiovascular Disease Event Risk for Patients Undergoing Major Non-Cardiac Surgery

The goal of this observational study is to learn whether the healthy lifestyle choices made around surgery can influence an individual's long term risk of developing cardiovascular disease. Patients will be observed 1-month prior to and 3-months following surgery to assess their risk of developing cardiovascular disease.

45 - 75 years of age All Phase N/A
Q Qianmei Zhu

Gut Microbiota and Pulmonary Complications After Non Cardiac Elective Surgery in Elderly Patients

This study adopts a combination of retrospective and prospective cohort research methods to explore the composition of preoperative oropharyngeal and gut microbiota in elderly patients undergoing elective upper abdominal surgery, aiming to analyze the correlation between preoperative oropharyngeal and intestinal microbiota composition and metabolite levels and the occurrence of postoperative …

65 years of age All Phase N/A
J Jayanta Chowdhury

MCID and PASS for Acute Pain and Quality of Recovery After Orthopedic Surgery

This study seeks to define what constitutes an MCID and a PASS in patients undergoing a variety of elective major orthopedic surgery.

18 - 80 years of age All Phase N/A

Neurocognitive and Genomic Predictors of Persistent Pain and Opioid Misuse After Spine Surgery

Having spine surgery and recovery is a vulnerable period when opioid naive patients may transition into long-term use of opioids, and when previously opioid tolerant patients may be at risk to continue towards long-term opioid use and dependence. However, little is known about risk for developing opioid misuse, taking opioids …

18 years of age All Phase N/A
M Martha DURAES, MD

Prevention of Postoperative Complications by Negative Pressure Therapy After Complex Breast Cancer Surgery

There is little scientific data concerning the use of negative pressure therapy after immediate breast reconstruction. That strategy of treatment-reconstruction has expanded increasingly since the last years. The current literature reports only 3 studies on the use of preventive negative pressure therapy in oncologic breast surgery. Moreover, all three are …

18 years of age Female Phase N/A

Ultrasound-assisted Spinal Anesthesia in Midline Versus Paramedian Approach in Adult Orthopedic Surgery

This study aims to compare between the two methods (midline and paramedian approach of spinal anesthesia guided by ultrasound) by the number of needle passes required to successful dural puncture.

18 - 50 years of age All Phase N/A
F Filomena RG Galas

Evaluation of Virtual Reality for Reducing Opioid Use After Cardiac and Thoracic Surgery

This clinical trial aims to evaluate the efficacy of virtual reality (VR) as an adjunctive therapeutic method to reduce opioid consumption during the postoperative period of cardiac and thoracic surgeries. Conducted at InCor/HCFMUSP, this single-center, prospective, randomized trial will include 60 patients aged 16 to 40 undergoing procedures such as …

16 - 40 years of age All Phase N/A
N Nilesh S Patil, MBBS, MS, M Ch

To Study Effect of Injection Pentoxifylline on Liver Growth After Major Liver Surgery

Posthepatectomy liver failure (PHLF) remains a significant life-threatening problem after major hepatectomies. Pentoxifylline is shown to have potent vasodilating properties for peripheral blood vessels, along with the hepatic vasculature. In a Double-blinded, randomized, controlled trial (RCT) at a single tertiary care center (2006-2009) by Petrowsky, Henrik et al (Annals of …

18 - 55 years of age All Phase N/A
X Xi Ma, MD

The Use of Islet Organoids in the Treatment of Pancreatic Surgery-related Diabetes

The purpose of this clinical trial is to verify the safety and effectiveness of autologous islet organoids transplantation after in vitro expansion for the treatment of pancreatogenic diabetes.

18 - 70 years of age All Phase N/A
C Clinical Research Coordinator or Clinical Research Specialist

Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery

The goal of this clinical trial is to determine if the drug Nizaracianine Triflutate can help surgeons see and avoid the ureters during abdominopelvic surgery. The ureters are thin-wall, collapsible tubes that connect the kidneys to the bladder. They are difficult to see during surgery and are sometimes damaged accidentally. …

18 years of age All Phase 2/3

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