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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,675 clinical trials

Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis

Objective To follow people with GISTs and collect tumor tissue so that it can be studied in the lab. Eligibility People age 6 and older who have a GIST. Design Participants will be screened with a review of their medical records and samples. Participants will enroll in 1 other NIH …

6 years of age All Phase N/A
J Joseph W Szokol, MD

Effect of Methadone and Hydromorphone on the QT Interval After Anesthesia and Surgery

A number of drugs used in the perioperative period may cause prolongation of the QT interval on the electrocardiogram (EKG). These drugs include inhalational agents, antiemetic agents, pain medications, and drugs used to reverse the effects of muscle relaxants. Approximately 80% of patients undergoing a general anesthetic will demonstrate significant …

18 - 80 years of age All Phase 4
M Muhammad Saad Yousuf, MBBS, FCPS

Effect of Methylprednisolone on Systemic Inflammatory Response During Pediatric Congenital Open-Heart Surgery

The goal of this study is to evaluate the effects of steroids on the early postoperative inflammatory response in patients undergoing elective pediatric congenital cardiac surgery, requiring cardiopulmonary bypass (CPB).

1 - 18 years of age All Phase 4
A Anton Kordonskiy, MD, PhD

Necessity of Fusion Following Decompression Surgery in Patients With Single-level Lumbar Stenosis

Long-term clinical results of two methods of surgical treatment (spinal decompression with or without fusion) in patients with single-level lumbar stenosis will be compared. A clear framework for surgical treatment methods and standardized postoperative rehabilitation treatment will be set to obtain the maximum homogeneity of the patient groups. This trial …

45 - 75 years of age All Phase N/A
B Behar Cohen Francine, Pr

Ursodeoxycholic Acid (UDCA) as a Neuroprotective Adjuvant Treatment to Rhegmatogenous Retinal Detachment Surgery

This study is indicated for patients with extended rhegmatogenous retinal detachment (RRD) (≥ 2 quadrants) with macula OFF lasting 7 days or less, pseudophakic or aphakic, and scheduled to undergo surgical intervention with vitrectomy and gas tamponade in one of the ophthalmology departments participating in the study. The main objective …

18 years of age All Phase 3

Ethyl Chloride Spray to Reduce Pain From Local Anesthesia During Mohs Micrographic Surgery

Fear of needles is a well-documented issue that affects many patients. This fear may cause significant anxiety in various medical situations, including in the dermatology office 1. If not properly managed, needle phobia can persist, affecting a patient's experience during each visit. This effect may compound and lead to avoidance …

18 years of age All Phase 0
A Anh Thi Nguyet Nguyen

Evaluating the Accuracy of Dynamic Navigation in Implant Surgery for Full Arch Prosthesis

Study Objective: This study aims to evaluate the accuracy of the Dynamic Navigation System in performing implant placement for full arch prosthesis rehabilitation. This system uses landmarks, including bone screws fixed to the bone (Group 1), and landmarks on remaining teeth to be extracted (Group 2), to accurately determine the …

18 years of age All Phase N/A
A Adrien Bouglé

Evaluation of the HPA Axis in Patients With Vasoplegic Syndrome After Cardiac Surgery

Vasoplegic syndrome after cardiac surgery is common and is associated with increased morbidity and mortality. It is characterized by early and prolonged arterial hypotension, with preserved cardiac output and low systemic vascular resistance. Vasoplegic syndrome therefore shares pathophysiological features with septic shock. There are no data in the literature on …

18 years of age All Phase N/A
T Therese Ramström, PhD

Comparing Upper Limb Surgery and Botulinum Toxin for Spasticity: A Paired Design Study

Spasticity is a common complication following central nervous system injuries. Left untreated, spasticity can lead to various complications, hindering activities of daily living and diminishing independence. Spasticity affecting the hand is particularly debilitating because it prevents prehension and grasp, which are critical factors for the ability to perform activities of …

18 years of age All Phase N/A
T Tuğçe Bozkurt Elmas, PhD(c)

The Effect of Virtual Reality and Eye Mask During Dressing After CABG Surgery

This study aims to evaluate the effects of virtual reality (VR) and eye mask (EM) applications on pain, anxiety, and physiological parameters during dressing after Coronary Artery Bypass Graft (CABG) surgery. Postoperative dressing procedures, especially after sternotomy, often cause significant pain and anxiety in patients. These issues can negatively impact …

18 - 65 years of age All Phase N/A

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