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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,675 clinical trials
M Martha DURAES, MD

Prevention of Postoperative Complications by Negative Pressure Therapy After Complex Breast Cancer Surgery

There is little scientific data concerning the use of negative pressure therapy after immediate breast reconstruction. That strategy of treatment-reconstruction has expanded increasingly since the last years. The current literature reports only 3 studies on the use of preventive negative pressure therapy in oncologic breast surgery. Moreover, all three are …

18 years of age Female Phase N/A

Ultrasound-assisted Spinal Anesthesia in Midline Versus Paramedian Approach in Adult Orthopedic Surgery

This study aims to compare between the two methods (midline and paramedian approach of spinal anesthesia guided by ultrasound) by the number of needle passes required to successful dural puncture.

18 - 50 years of age All Phase N/A
N Nilesh S Patil, MBBS, MS, M Ch

To Study Effect of Injection Pentoxifylline on Liver Growth After Major Liver Surgery

Posthepatectomy liver failure (PHLF) remains a significant life-threatening problem after major hepatectomies. Pentoxifylline is shown to have potent vasodilating properties for peripheral blood vessels, along with the hepatic vasculature. In a Double-blinded, randomized, controlled trial (RCT) at a single tertiary care center (2006-2009) by Petrowsky, Henrik et al (Annals of …

18 - 55 years of age All Phase N/A
X Xi Ma, MD

The Use of Islet Organoids in the Treatment of Pancreatic Surgery-related Diabetes

The purpose of this clinical trial is to verify the safety and effectiveness of autologous islet organoids transplantation after in vitro expansion for the treatment of pancreatogenic diabetes.

18 - 70 years of age All Phase N/A
R Robert Coffee

A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults

The purpose of this study is to collect data about local versus general anesthesia for inguinal hernia repair in Veterans aged 60 years for planning a larger, multisite randomized clinical trial. Approximately 80 participants will be enrolled and can expect to be on study for 6 months.

60 years of age All Phase N/A
M Michelle E Fullard

Evaluation of a Decision Aid for Deep Brain Stimulation Surgery for Parkinson's Disease

The goal of this clinical trial is to learn if a Decision Aid can help patients with Parkinson's disease make a decision about undergoing Deep Brain Stimulation surgery. The main questions it aims to answer are: Is the Decision Aid acceptable to patients with Parkinson's disease considering Deep Brain Stimulation …

18 years of age All Phase N/A
C Clinical Research Coordinator or Clinical Research Specialist

Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery

The goal of this clinical trial is to determine if the drug Nizaracianine Triflutate can help surgeons see and avoid the ureters during abdominopelvic surgery. The ureters are thin-wall, collapsible tubes that connect the kidneys to the bladder. They are difficult to see during surgery and are sometimes damaged accidentally. …

18 years of age All Phase 2/3

Time to Return of Bowel Function Following Perioperative Probiotics in Colorectal Cancer Surgery

There is pre-existing evidence that probiotics could be useful in the improvement of ileus rates. One metaanalysis of 30 studies demonstrated a reduction in the prevalence of post-operative ileus as determined by time to flatus, time to defecation, as well as postoperative abdominal distension (PMID:37373843). More broadly in gastrointestinal surgery, …

21 - 99 years of age All Phase N/A
N Nils Prenzler, Dr.

Intracochlear Application of VSF1.01 for the Reduction of Cochlear Implant Surgery Related Trauma

The goal of this clinical trial is to assess the safety of intracochlear application of VSF1.01 for the reduction of cochlear implant surgery related trauma in patients with profound hearing loss with or without non-functional residual hearing in low frequencies and cochlear implantation. The main questions it aims to answer …

18 years of age All Phase 1/2
M Mohamed ElMeligie, Ph.D

Timing of Specific Exercise Therapy After Breast Cancer Surgery: Early Versus Delayed Initiation

This single-center, parallel-group randomized controlled trial (RCT) will compare two timings for initiating specific exercise therapy after breast cancer surgery. The study tests whether early initiation (within the first postoperative week) versus delayed initiation (at 3 weeks postoperative) results in superior upper limb function at 6 months as measured by …

18 - 65 years of age All Phase N/A

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