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hearing-loss Clinical Trials

A listing of hearing-loss medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 164 clinical trials
I Isabelle Dr MOSNIER, MD

Deafness and Cognition in Middle-aged Adults

A mild cognitive impairment was observed in 50% of cochlear implant candidates aged 65 years and over, compared to 5-19% in general population. No studies analysed cognition in patients younger than 65 years. The aim of our study was to compare cognitive function between patients with severe and profound hearing …

45 - 64 years of age All Phase N/A
B BANG-YAN ZHANG

The Role of Migraine Prophylaxis Agent Topiramate in Treating Patients With Sudden Sensorineural Hearing Loss

Migraine and sudden sensorineural hearing loss(SSNHL) are two related disorders. A systemic steroid is usually used to treat SSNHL but the role of migraine prophylaxis medication remained unknown. Mehdi Abouzari et al. found a better improvement when combining topiramate and nortriptyline with steroids in a retrospective study. However, a prospective …

20 years of age All Phase 2
J Javier Gavilán

Subjective and Audiological Benefit of BONEBRIDGE (BCI602) With Two Different Fitting Strategies

The Bonebridge (BB) is a partially implantable active transcutaneous bone conduction hearing system manufactured by MED-EL Elektromedizinische Geräte Gesellschaft m.b.H. (MED-EL, Innsbruck, Austria). The BB augments hearing by providing acoustic input to the inner ear via bone conduction. In 2017 Hodgetts & Scollie introduced a new fitting algorithm called DSL-BCD. …

18 years of age All Phase N/A
A Alexandre Karkas, Pr

Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Bimodal Fitting and a Conventional Fitting

Main objective: For a bimodal fitting (hearing aid (HA) + cochlear implant (CI)): Comparison of a tonotopy based fitting strategy (TFS4) to a default fitting strategy (FS4) for the speech recognition in noise. Secondary objectives: Comparison of TFS4 to FS4 for speech recognition in quiet. Comparison of TFS4 to FS4 …

18 years of age All Phase N/A
H HAIQIAO DU, PhD

Evaluation of Rehabilitation Results in the Single-sided Deafness With Cochlear Implantation

Single-sided deafness (SSD) refers to severe to profound sensorineural hearing loss on one side (average pure-tone hearing threshold≥70 dB HL at 0.5, 1, 2, and 4kHz) while the opposite side maintains normal hearing or mild hearing loss (30 dB HL). Asymmetrical hearing loss (AHL) refers to severe to profound sensorineural …

12 years of age All Phase N/A
I Ingeborg Dhooge

Evaluation of the CochSyn Test Prototype to Measure Cochlear Synaptopathy

This study investigates a newly developed test, The CochSyn test that can quantify cochlear synaptopathy (CS) (a new type of sensorineural hearing loss (SNHL)) earlier than the current golden standard pure-tone audiogram.This newly developed test is based on auditory evoked brain potentials. A hardware prototype (the Cochsyn test prototype) was …

18 - 87 years of age All Phase N/A
D Dawna E Lewis, Ph.D.

Vocal Emotion Communication With Cochlear Implants

Patients with hearing loss who use cochlear implants (CIs) show significant deficits and strong unexplained intersubject variability in their perception and production of spoken emotions in speech. This project will investigate the hypothesis that "cue-weighting", or how patients utilize the different acoustic cues to emotion, accounts for significant variance in …

6 - 80 years of age All Phase N/A
I Isabelle Dr MOSNIER, MD

Cochlear Implanted Listening Effort and Hearing Attention

Cochlear implant users perceive mainly sound amplitude modulation cues. Processing of these amplitude modulations can be subject to interferences, so that the perception of a modulation in a target sound can be impaired by a superimposed sound if this sound contains a similar modulation. Such phenomenon, which is observed both …

18 - 80 years of age All Phase N/A
H Hans GXM Thomeer, MD, PhD

Hearing Preservation in Cochlear Implantation Surgery

In order to preserve the residual hearing in patients with sensorineural hearing loss (SNHL) receiving a cochlear implant (CI), the insertion trauma to the delicate and microscopic structures of the cochlea needs to be minimized. The surgical procedure starts with the conventional mastoidectomy-posterior tympanotomy (MPT) approach to the middle ear, …

18 years of age All Phase N/A
N Nicole M. Tombers, RN

Pivotal Clinical Trial Evaluating the Safety and Efficacy of the Fully Implanted Acclaim Cochlear Implant

The goal of this clinical trial is to learn if the Acclaim CI works to treat severe to profound sensorineural hearing loss in adults. It was also learn about the safety of the Acclaim CI implant. The main questions it aims to answer are: Does the Acclaim CI device help …

18 years of age All Phase N/A

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