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hearing-loss Clinical Trials

A listing of hearing-loss medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 169 clinical trials
J Javier Gavilán

Subjective and Audiological Benefit of BONEBRIDGE (BCI602) With Two Different Fitting Strategies

The Bonebridge (BB) is a partially implantable active transcutaneous bone conduction hearing system manufactured by MED-EL Elektromedizinische Geräte Gesellschaft m.b.H. (MED-EL, Innsbruck, Austria). The BB augments hearing by providing acoustic input to the inner ear via bone conduction. In 2017 Hodgetts & Scollie introduced a new fitting algorithm called DSL-BCD. …

18 - 100 years of age Both Phase N/A
W Wan-Cian Liao

Gene Therapy Trial for Otoferlin Gene-mediated Hearing Loss

Part A of this trial will evaluate the safety and tolerability of a single unilateral administration of one of two dose levels of AAVAnc80-hOTOF and will evaluate the Akouos delivery device to safely achieve the intended product performance.

- 100 years of age Both Phase 1/2
M Manohar Bance, FRCSC

A Study of DB-OTO, an Adeno-associated Virus (AAV) Based Gene Therapy, in Children/Infants With Hearing Loss Due to Otoferlin Mutations

Regeneron is conducting a study of an investigational new drug called DB-OTO. DB-OTO is a gene therapy that is being developed to treat children who have hearing loss due to changes in the otoferlin gene. The purpose of this study is to: Learn about the safety of DB-OTO Determine how …

- 17 years of age Both Phase 1/2
I Imran Amjad, Phd

Effects of Pilates and Balance Proprioception Exercises on Hearing Impairment

Static balance is the ability to hold the body in a specific position and posture, while dynamic balance is the ability to maintain balance while moving. Vision, somatosensation, vestibular, and hearing are integrated to achieve balance Ethical committee approval will be obtained. A written consent will be taken from all …

10 - 14 years of age Both Phase N/A
B Busra Kepenek-Varol, PhD, PT

Core Stabilization Training on Chest Expansion, Functional Capacity, Trunk Muscle Endurance in Hearing-Impaired Children

Children's motor skills and physical performance increase with age due to the development of neuromuscular and cardiorespiratory systems. Sensory impairment seen in children with hearing loss can cause balance and coordination disorders, as well as decreased muscle strength and respiratory functions. Anatomically, core stabilization is provided by the diaphragm, abdominal, …

10 - 15 years of age Both Phase N/A
H Haera Han

K-HEARS MCI: Hearing Health Care for Korean American Older Adults With Mild Cognitive Impairment

The objective of this study is to develop and assess the feasibility, acceptability, and preliminary efficacy of a community-delivered, affordable, and accessible hearing care intervention tailored to the needs of community-dwelling Korean American (KA) older adults with mild cognitive impairment (MCI) and their care partners that integrates a low-cost over-the-counter …

60 - 100 years of age Both Phase N/A

A Study of Objective Fitting for Focused Multipolar Stimulation

The purpose of this exploratory study is to trial various objective and behavioural fitting methods for potential use with Focused Multipolar Stimulation programming.

18 - 100 years of age Both Phase N/A
K Kristin Montella

Auditory Brainstem Implant (ABI) in Children With No Cochleae or Auditory Nerves

This study is a feasibility study of the Nucleus 24 ABI in children without NF2. It will be conducted as a repeated-measures, single subject experiment in order to accommodate the known variability in cochlear implant clinical results. Data obtained in the course of this study will be compared with the …

18 - 21 years of age Both Phase N/A
M Margaret Dillon, Au.D

Single-Sided Deafness in the Medicare Population

The purpose of this study is to evaluate the safety and effectiveness of cochlear implantation in adults 65 years of age and older.

65 - 100 years of age Both Phase N/A
J Jareen Meinzen-Derr, PhD

Technology-assisted Language Intervention (TALI)

This study is testing the effectiveness of augmentative and alternative communication technology among deaf or hard of hearing children for improving language development. Children will be randomized to receive either the technology intervention or treatment as usual

3 - 10 years of age Both Phase N/A

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