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hearing-loss Clinical Trials

A listing of hearing-loss medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 163 clinical trials
J Jane Sheehan

Improving Early Intervention in Hearing Impaired Children Using Functional Near-Infrared Spectroscopy (fNIRS)

The goal of this clinical trial is to find out whether hearing test results using functional near-infrared spectroscopy (fNIRS) will help to fast-track early intervention for infants born with a hearing loss. fNIRS is a method of imaging brain activity using light. The main questions are: Can audiologists make more …

24 years of age All Phase N/A

Evaluating a Noise Reduction Algorithm With Cochlear Implant Users

In this study, a noise reduction algorithm will be implemented in various listening situations to evaluate its effectiveness in improving speech understanding for cochlear implant users ages 12 and older.

12 years of age All Phase N/A
B Barbara Vona, PhD

Otoferlin Patient Registry and Natural History Study

This registry is designed to collect comprehensive information about the molecular genetic diagnoses of individuals with otoferlin-associated hearing impairment and clinical information to support a natural history study.

years of age All Phase N/A

Clinical Evaluation of Frequency Allocation for Bimodal CI Users

This study will examine experienced, bimodal cochlear implant (CI) patients who receive an alternative frequency allocation table (FAT) to determine how it improves sound quality, device satisfaction, and speech perception abilities with respect to the standard default FAT. The goal of this study is to investigate how improving place-pitch mismatch …

18 years of age All Phase N/A
B Barbara Vona, PhD

CABP2 Patient Registry and Natural History Study

This registry is designed to collect comprehensive information about the molecular genetic diagnoses and clinical information of individuals with CABP2-associated hearing impairment to support a natural history study.

years of age All Phase N/A
S Sari M Kunnari, PhD Professor

ListenFuture-Listening for Their Future: Deaf and Hard-of-Hearing Adolescents

ListenFuture, a nation-wide multidisciplinary project, brings new knowledge on complex associations between listening, cognition, language, literacy, and psychosocial wellbeing in deaf and hard-of-hearing (DHH) adolescents. Earlier findings indicate that DHH adolescents remain at a risk to achieving age-appropriate skills. The associations among these skills can also be language-dependent. The investigators …

11 - 16 years of age All Phase N/A
L Leslie Stevens

Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness

The aim of the study is to assess the continued efficacy and safety of cochlear implantation in participants aged 5 years and above with Unilateral Hearing Loss (UHL)/Single Sided Deafness (SSD) supporting a change indication for use.

5 years of age All Phase N/A
R Rongqun Zhai, Dr.

A Study of EH002 Gene Therapy for Otoferlin Gene Mutation-mediated Hearing Loss

The study is designed to evaluate the safety, tolerability, and preliminary efficacy of EH002 for the treatment of congenital deafness caused by mutations in the OTOF gene. Participants may receive one or two injections of the EH002 gene therapy in one or both ears.

6 years of age All Phase N/A
S Su Htwe

Effects of Bisphosphonates on OI-Related Hearing Loss

Osteogenesis Imperfecta-related hearing loss usually occurs in individuals with mild (type I) OI and is much earlier in onset than age-related hearing loss, with the majority of individuals experiencing some minor hearing loss in their 20s. Bisphosphonates have been successfully used to treat otosclerosis, a common cause of hearing loss …

6 - 100 years of age All Phase 4
E Eva Orzan, MD

Hearing Impairment in Children: Pupillometry and Hearing Thresholds Assessment

The results of the previous study on auditory effort in young children with cochlear implants show that pupils respond to the presence or the absence of the perceived stimuli. The investigators hypothesize that the perceived sounds will elicit increased pupil dilation compared to the non-perceived sounds and that the hearing …

4 - 36 years of age All Phase N/A

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