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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,778 clinical trials

Transcutaneous Electrical Nerve Stimulation (TENS) and Low Back Pain

Low back pain is a significant public health problem, is very prevalent, and is often characterized by the persistence of symptoms. Unfortunately, substantial improvements in people with chronic low back pain are rare, causing most people to live with the pain. People with chronic low back pain may have an …

18 - 60 years of age All Phase N/A
K Krishnan Venkatesan, MD

Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty

Patients undergoing buccal urethroplasty will often have significant post-operative oral pain from the graft site. Various graft harvest techniques and methods for post-harvest hemostasis including graft site closure have been explored. Despite the frequency of this clinical scenario there is no established best practice for peri-operative pain management in this …

18 years of age Male Phase 3
J J. A.C. Verbunt, MD, PhD

Chronic Pain Rehabilitation in Patients With Small Fiber Neuropathy

Small fiber neuropathy (SFN) is a condition that is dominated by invalidating neuropathic pain. Pharmacological neuropathic pain treatment is often disappointing, since pain reduction is mostly slight and side effects can be debilitating. Although neuropathic pain is caused by a lesion of the somatosensory system, also psychological factors, such as …

18 years of age All Phase N/A
V Verena E Hofmann, M. Sc.

Personalising Psychotherapy for Chronic Primary Pain Using Network Analysis

The goal of this single case experimental design study with multiple baselines is to use network analysis to personalise cognitive behaviour therapy for chronic primary pain (CPP) and base the selection of individual treatment targets and interventions on data to avoid cognitive biases of the clinicians. The main questions it …

18 years of age All Phase N/A
Y Yara Agbaria, MSc

The Impact of THC on Pain Modulation in Fibromyalgia

The objective of this cross-sectional, double-blind, placebo-controlled clinical trial is to enhance our understanding of the pain modulation mechanisms in females diagnosed with Fibromyalgia syndrome (FMS). This study is designed to address several key questions: Is there a discernible difference in the effectiveness of the two prevalent pain modulation approaches, …

20 - 60 years of age Female Phase N/A
M Michael Bøndergaard, MD

Intraoperative Methadone for Postoperative Pain in Patients Undergoing Tonsillectomy

A randomized controlled trial evaluating the efficacy and safety of single-shot intraoperative methadone for postoperative pain in patients undergoing tonsillectomy. Fentanyl is used as an active comparator

18 - 100 years of age All Phase 4

Pre-habilitation Interventions to Empower Patients With Chronic Pain

The development of alternative methods to address simple clinical needs and easy interventions of self-application are desired in the pre-habilitation period (waiting list). To our knowledge that are very few studies regarding interventions for patients in waiting list for specialized treatment of chronic non-cancer pain (CNCP) and they do not …

18 years of age All Phase N/A
P Patricia Martinez-Merinero, PhD

Dry Needlig Vesus Tecartherapy in Low-back Pain Treatment

Introduction: Diathermy is a new tool that could help subjects with chronic low back pain (CLBP), with no studies having compared it to other interventions already investigated such as dry needling. Hypothesis: Diathermy is more effective than dry needling in improving pain intensity in the short term in subjects with …

18 - 65 years of age All Phase N/A
M Margaret A. Gettis, DNP,CPNP-PC

Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy

The purpose of this pilot study: 1) to examine the use of gabapentin in reducing pain in the first 48 hours postoperatively including the total amount of narcotics mg/kg given 2) to record the time to first analgesic postoperatively and 3) to compare Wong Baker and the 0-10 numeric pain …

3 - 18 years of age All Phase 4
J Joshua Vernon

Chronic Widespread Pain in HIV: Novel Mechanisms and Therapeutics

To determine if decreased production or release of endogenous opioid peptides by peripheral immune cells contributes to hypersensitivity in people with HIV

19 - 65 years of age All Phase N/A

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