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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,757 clinical trials
K Karim Ladha, MD MSc FRCPC

Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN

This is a feasibility study to examine the use of use of Psilocybin (magic mushrooms) to alleviate pain in chronic neuropathic pain. While theoretical mechanisms demonstrate promise, there is no clinical evidence. This vacuum of clinical evidence has been occupied by a "psychedelic hype bubble" with media communications touting psychedelics …

18 - 65 years of age All Phase 2
G Gayathri Subramanian

Twin Block, Pain Medications and Third Molar Extractions

Each year, over 3.5 million, mostly, healthy young adults, have their third molar teeth ('wisdom teeth') removed under sedation and are often given opioid prescriptions for managing their pain. Wisdom molar removal is one of the most common reasons for opioid prescriptions to be given to adolescents. There is a …

18 years of age All Phase 2
E Elika Fanaeian

Magnesium as an Adjuvant Agent for Postoperative Pain

Participants are being asked to participate in this research study because they have elected to undergo periacetabular osteotomy (PAO). This research study is looking at if using IV magnesium during surgery can help to reduce pain after surgery.

14 - 89 years of age All Phase 4
J Jordan University Hospital

Influence of Occlusal Reduction on Endodontic Postoperative Pain

This study aims to assess the impact of occlusal reduction on post-operative pain after single-visit root canal treatment in patients with necrotic pulps or previously initiated (accessed).

18 - 70 years of age All Phase N/A
A Annette B. Hickerson, RN, CCRC

Pain With Differing Insufflation Pressures During Laparoscopic Hysterectomy

The purpose of this study is to determine the effect of decreased insufflation pressure on postoperative pain, analgesic use, and surgical safety and feasibility for laparoscopic hysterectomy.

18 - 80 years of age Female Phase N/A

JIT: Effect of Pain on DT in TMD

Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in many individuals. However, few systematic examinations of modifiable and non-modifiable risk factors, including orofacial pain status, have been …

21 - 65 years of age All Phase N/A

Integrative Training Program for Pediatric Sickle Cell Pain

This research aims to answer the question: does a group training program specifically for teens with chronic sickle cell disease (SCD) pain that teaches skills to strengthen the mind and body help improve everyday functioning and reduce pain symptoms? The program will be tailored to address challenges related to frequent …

12 - 18 years of age All Phase N/A
A Ammani Brown, BA (Hons) MSc

Neurofeedback for Nociplastic Pain in Rheumatoid Arthritis (NECTAR)

Rheumatoid arthritis is an autoimmune condition, causing inflammation and pain. Yet pain may persist even when inflammation has been treated. This residual pain, called nociplastic pain, has symptoms of a chronic pain condition called fibromyalgia. There are few effective therapies to address this residual pain. Published literature shows that fibromyalgia …

18 - 75 years of age All Phase N/A
L Lory Abrahamian

Factors Influencing Postoperative Pain After Gingival Graft Harvesting

This prospective cohort study aims to evaluate patient-related, psychological, and clinical factors influencing postoperative pain following gingival graft harvesting from the palate. Consecutive adult patients requiring mucogingival surgery for root coverage or soft tissue augmentation around teeth or dental implants will be recruited at the Clínica Universitària d'Odontologia of Universitat …

18 years of age All Phase N/A
C Christian Becker, MD

Predicting the Pain Outcome of Surgery for Endometriosis

This study aims to determine whether the investigators can predict who will get benefit in terms of their pain from surgery for more severe forms of endometriosis. The investigators will use brain imaging to explore this, as it allows meaningful results from a smaller sample of people than if questionnaires …

18 - 50 years of age Female Phase N/A

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