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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,778 clinical trials

Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy

The objective of this study is to conduct a randomized clinical trial to evaluate an opioid versus an opioid-free pathway of perioperative use of ketamine, ketorolac, and IV acetaminophen followed by the postoperative use of ketorolac, and oral acetaminophen for pain associated with robotic-assisted radical prostatectomy. Escalation to use of …

40 - 75 years of age Male Phase 2/3
A Anastasia Keller, PhD

Transcutaneous Spinal Cord Stimulation for Chronic Low Back Pain

As a leading cause of disability worldwide, chronic low back pain (cLBP) represents a significant medical and socioeconomic problem with estimated health care spending of $87 billion/annually. The efficacy of dorsal column electrical stimulation to inhibit pain was first described over 50 years ago. Since then, several large clinical trials …

21 - 85 years of age All Phase N/A
S ST-CP-201 Study Clinical Trials Coordinator

Sustained Release Lidocaine for the Treatment of Postoperative Pain

In this study, the investigators are testing a new formulation of lidocaine for its suitability in managing postoperative pain after pelvic (circumcision, inguinal, scrotal), perineal (hemorrhoidectomy) or perianal (fistulotomy) incisions. The new formulation ST-01 is a sustained release lidocaine formulation and is expected to provide pain relief over multiple days. …

19 years of age All Phase 2
Ş Şerife Tutar

Reducing Pain During Heel Blood Collection in Preterm Newborns

Pharmacological and non-pharmacological methods are used to control interventional pain in preterm newborns. Non-pharmacological methods should be preferred in the management of pain, especially during painful minor invasive procedures (blood collection, orogastric tube insertion, aspiration, etc.) applied during the day. Some of these methods are; kangaroo care, breast milk, fetal …

3 - 5 years of age All Phase N/A
m maryam shoaib, DPT

Comparison of Concentric-eccentric Exercises in Patellofemoral Pain Syndrome

Patellofemoral pain syndrome is due to dysfunctional dynamic knee valgus resulting from decrease in strength of hip abductors or abnormal rear-foot eversion with pes pronatus valgus. It is also associated with vastus medialis/vastus lateralis disbalance, hamstring tightness or iliotibial tract tightness.

18 - 36 years of age All Phase N/A
C Chunling Jiang, PhD

Intravenous Lidocaine on Chronic Pain in Patients Undergoing Hepatectomy

This study is a further observation and follow-up of the patients enrolled in the registration number NCT04295330 to further evaluate the effect of long-term infusion of lidocaine on postoperative chronic pain, long-term quality of life and survival rate in patients undergoing liver cancer surgery.

18 - 80 years of age All Phase 2
N Neil Lagali

Alternating and Direct Current Stimulation for Neuropathic Eye Pain

The goal of this clinical intervention is to test if two forms of transcranial current stimulation, transcranial direct current stimulation (tDCS) or transcranial alternating current stimulation (tACS) can alleviate neuropathic eye pain in a sample of 20 patients. The main aims are: Test if tDCS/tACS can alleviate neuropathic eye pain …

18 years of age All Phase N/A
S Sarah L Krein, PhD RN

Self-Administered Acupressure for Veterans With Chronic Back Pain

Many Veterans experience chronic pain, with back pain the most commonly reported condition. The Veterans Health Administration (VHA) is moving from reliance on medications to an approach in which non-medication interventions, including complementary and integrative health treatments, are now a first line of care. Acupressure, a Traditional Chinese Medicine technique …

18 years of age All Phase N/A
J Jennifer Deluca

Explosive Synchronization of Brain Network Activity in Chronic Pain

This project is being conducted to evaluate the impact of explosive synchronization (ES) and its treatment with non-invasive brain stimulation in fibromyalgia (FM). The study design has three components, however, only 2 aims are enrolling participants. The first part (Aim1) is a cross sectional assessment of brain network explosive synchronization …

19 - 74 years of age All Phase N/A
P Petter C Borchgrevink, md prof

Radiofrequency Neurotomy for Chronic Facet Joint Related Neck Pain

This is a single-center, double blind, sham-controlled randomized trial (N: 34) to assess the long term efficacy of RF neurotomy of cervical medial branches. Patients with chronic unilateral neck pain who are found eligible and achieve ≥50% pain relief of two predictive and comparative test blocks will be included in …

18 - 80 years of age All Phase N/A

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