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Knee Replacement Clinical Trials

A listing of Knee Replacement medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 213 clinical trials
M Marco Attanasio, Dr

GMK Sphere TiNb Total Knee Arthroplasty PMS Study

Total knee arthroplasty (TKA) is one of the success stories of modern surgery, providing high patient satisfaction outcomes. Total knee prostheses are generally composed by a femoral component articulating on a polyethylene insert and a tibial tray. Recently there has been particular attention on the component material; traditionally femoral components …

18 years of age All Phase N/A

Clinical Utility and Gait Analysis of NextAR System AUS

This study titled "Does Personalised Soft Tissue Balance Data Improve Outcomes in Patients Undergoing Medially Stabilised Arthroplasty? A Prospective, Randomised Study Investigating the Clinical Utility of the NextAR navigation system (NextAR)" is a randomised, single blinded, prospective cohort study with the primary aim determine the clinical utility of the NextAR …

18 years of age All Phase N/A
M Maedeh Mansoubi, PhD

Knee4Life Project: Empowering Knee Recovery After Total Knee Replacement Through Digital Health

The research project will investigate the extent to which a smartphone camera sensor tool can help predict and measure knee stiffness and pain after Total Knee Replacement Surgery (TKR) and how a tool such as this could be implemented into the NHS. Total knee replacement (TKR) is a frequent procedure …

18 years of age All Phase N/A
B Brita Stanghelle, PhD

Maximal and Self-selected Walkingspeed After Knee Arthroplasty - a Prospective Cohort Study

The purpose of this prospective study is to explore whether maximal and self-selected walking speed in individuals with knee arthroplasty is a useful and applicable clinical measure that can provide new insights into physical function after prosthetic surgery. We will examine the progression of walking speed and other measures of …

55 years of age All Phase N/A

VRAS (Velys Robot-Assisted Solution) Operational Excellence Study

The aim of this study is to investigate the differences in process set-up, efficiency, OR team workload, instrument trays and OR financial performance when using the VRAS (Velys Robotic Assisted Solution) of DePuy Synthes compared to conventional TKA.

18 - 100 years of age All Phase N/A
B Bart Stuyts, Dr.

A Post-market Observational ORIGIN® CR Clinical Study

The study objective is to evaluate safety and performance of the ORIGIN® CR (cruciate retaining) devices and associated instruments, more precisely to evaluate safety by the proportion of patients requiring a revision (i.e. revision rate) at 1-year post procedure and to evaluate performance by means of a Knee Society Score …

18 - 99 years of age All Phase N/A

Comparison of Different Analgesic Nerve Blocks in Total Knee Replacement Surgery

The goal of this observational study is to compare the equivalent analgesic efficacy of three regional anesthesia techniques in total knee replacement surgery. The main question it aims to answer is: • Non inferiority of each technique in relation to the others Participants will receive selective spinal anesthesia and the …

18 years of age All Phase N/A
M MAHMUT S TUTAR

Heart Rate Variability as a Predictor of Rebound Pain Following Total Knee Arthroplasty

This study aims to investigate whether heart rate variability (HRV), a marker of autonomic nervous system activity, can predict the occurrence of rebound pain after total knee arthroplasty (TKA). Rebound pain is defined as a sudden and intense pain episode (NRS ≥7) that typically arises after the resolution of peripheral …

18 - 70 years of age All Phase N/A
J Joel Pollet

Frailty in Hip or Knee Arthroplasty Patients.

The study aims to understand the existing differences between frail and non-frail subjects who underwent a rehabilitation path after receiving hip or knee arthroplasty surgery.

18 years of age All Phase N/A
M Milan Mohammad, MD

Characteristics of Persistent Pain Composition Following Total Hip or Knee Arthroplasty: a Descriptive Study

Despite high success rates of hip and knee arthroplasty, up to 20% of patients report moderate-to-severe pain (NRS > 3) persisting beyond the expected healing period. This investigator-initiated, descriptive cohort study will re-invite approximately 100 consenting patients with persistent postoperative pain-identified from a pool of ~7 000 respondents-to complete standardized …

18 years of age All Phase N/A

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