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Knee Replacement Clinical Trials

A listing of Knee Replacement medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 205 clinical trials
I Irene LOPERA, PRINCIPAL INVESTIGATOR

Effectiveness of a Prehabilitation Program for Hip or Knee Arthroplasty Surgery.

We live in an increasingly aging society in which the incidence of osteoarticular diseases increases, among which osteoarthritis (OA) stands out. OA is a degenerative disorder of the different components of the joint leading to a progressive destruction of the same. The hip and knee being the most affected joints, …

45 - 80 years of age All Phase N/A
M Malgorzata Domagalska, Ph.D.

Dexamethasone Vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty

Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for knee arthroplasty

18 - 100 years of age All Phase 4
S Stefano Zaffagnini, MD

Assessment of Periprosthetic Bone Mineral Density in Patients Undergoing Total Knee Prosthesis of Different Design

compare changes in BMD via DXA at the level of the femoral and tibial periprosthetic bone between two groups of patients undergoing cemented TKA of different design (posterior stabilization vs posterior cruciate preservation) with proms at a 2-year follow-up.

45 years of age All Phase N/A

Investigating the Role of Motivational Interviewing in Swedish Patients Undergoing Knee Arthroplasty

Knee arthroplasty is a successful surgical treatment for end-stage osteoarthritis. Most patients are satisfied with the result, however, 10% of the patients have remained dissatisfied over the last decades despite the advantages of the surgical procedure. Previous studies suggest that rehabilitation needs to be individualized and that some patients request …

years of age All Phase N/A
H Hermann dos Santos Fernandes, MD, PhD

Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine

Revision total knee arthroplasty (rTKA) is a frequently performed procedure. Adequate pain management is an important feature, especially for fast-track and Enhanced Recovery After Surgery (ERAS) programs. The multimodal approach, including single shot or continuous nerve blocks with catheters and spinal or epidural morphine, is a stablished strategy. Although the …

21 years of age All Phase 3
P Pascal Bizot

Evaluation of a New Bi-Condylar Total Knee Prosthesis (TKP) With All-Ceramic Friction (The Forgotten Knee)

The results of TKP (Total Knee Prosthesis) are satisfactory but do not reach those of THP (Total Hip Prosthesis) in terms of indolence and function. By using an all-ceramic friction torque, identical to that of the hip, the promotor of this Clinical Investigation expects to obtain an improvement in term …

18 - 70 years of age All Phase N/A
z zeliha tuncel, ass prof

Investigation of the Effect of Proximal and Distal Adductor Canal Block in Knee Replacement Surgery

to investigate the effect of adductor canal block applied with two different approaches in the treatment of pain after TKA surgery on pain control and functional mobility.

18 - 85 years of age All Phase N/A
M Malgorzata Reysner, M.D. Ph.D.

Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty

"The Effect of Dexamethasone Administration Route on Pain and Inflammatory Response in iPACK With ACB for Total Knee Arthroplasty" - written in plain language according to ClinicalTrials.gov standards: The goal of this clinical trial is to learn how the route of dexamethasone administration (either through the vein or nerve block) …

65 - 100 years of age All Phase 4
M Mesut Çimen, Supervizor

Effects of Different Relaxation Therapies on Pain and Sleep in Hip and Knee Arthroplasty Patients

Hip and knee replacement surgery is commonly performed in older adults. After surgery, many patients experience pain, limited movement, and sleep problems. These difficulties can make daily activities such as walking or climbing stairs more challenging and may reduce quality of life during recovery. Relaxation exercises are often used to …

18 years of age All Phase N/A
C Clinical Research Coordinator

Real-component Vs All-cement Articulating Spacers for Periprosthetic Knee Infection

In the US, if an infection in an artificial knee joint doesn't heal with antibiotics alone, the standard treatment is a two-stage revision of the artificial knee. In the first stage, the surgeon will remove the artificial knee and clean out the area around the knee. They will then place …

18 years of age All Phase N/A

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