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Knee Replacement Clinical Trials

A listing of Knee Replacement medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 221 clinical trials
C Cesare Faldini, MD

FAldini Sport Total Joint Arthroplasty-Knee II

The majority of patients undergoing total knee arthroplasty are elderly individuals with low functional demands, aiming to alleviate pain. However, there exists a subgroup of younger patients, under the age of 65, with higher functional demands. The purpose of this study is to evaluate the return to sports activities in …

40 - 65 years of age All Phase N/A

FitJoints: Getting Fit for Hip and Knee Replacement

Total hip or knee replacement is an important and cost-effective surgical intervention to relieve pain and improve independence and function in patients with osteoarthritis. The number of people waiting for elective surgeries has spiked in the COVID-19 pandemic. Prior to COVID-19, up to 40% of patients receiving joint replacement were …

60 years of age All Phase N/A
H Hilde Vandenneucker

Determinants for Return to Work After Primary Knee Arthroplasty

The increase of end-stage osteoarthritis (OA) in an increasingly younger population is directly correlated with the rising incidence of obesity. As a result, knee arthroplasty (KA), which is a definitive end-stage treatment option, is increasingly performed on working age people. Knowledge and understanding of the underlying factors that drive the …

18 - 63 years of age All Phase N/A
A Alev Keskin

Effect of Foot Massage on Pain and Analgesic Consumption in Total Knee Prosthesis

This randomized controlled trial aims to examine the effects of foot massage combined with cold application on postoperative pain, patient satisfaction, and analgesic consumption in individuals undergoing Total Knee Arthroplasty (TKA). The study will be conducted in the Orthopedics and Traumatology Department of Çukurova University Balcalı Hospital, which includes an …

18 years of age All Phase N/A
D Direzione Scientifica

Functional Recovery After Medial Monocompartmental Knee Prosthesis: One Day Protocol Versus Fast Protocol

The study is defined as prospective, randomized, interventional single-center; the general aim is to evaluate the post-operative recovery of the patient who carries out rehabilitation with the one day protocol (Group A), compared to the patient who carries out rehabilitation during the hospital stay with the fast protocol (group B).

40 - 85 years of age All Phase N/A
L Laura Mangiavini

Effects of Tele-prehabilitation in Patients Waiting for Knee Replacement

After knee arthroplasty rehabilitation is fundamental to patient's functional recovery, but in recent years there has been a growing interest in the possibility to prepare patients for surgery through a "prehabilitation" program. This two-parallel groups randomized clinical trial aims at evaluating the effects of a preoperative rehabilitation programme carried out …

65 - 80 years of age All Phase N/A
M Malgorzata Domagalska, Ph.D.

Dexamethasone Vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty

Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for knee arthroplasty

18 - 100 years of age All Phase 4
I Irene LOPERA, PRINCIPAL INVESTIGATOR

Effectiveness of a Prehabilitation Program for Hip or Knee Arthroplasty Surgery.

We live in an increasingly aging society in which the incidence of osteoarticular diseases increases, among which osteoarthritis (OA) stands out. OA is a degenerative disorder of the different components of the joint leading to a progressive destruction of the same. The hip and knee being the most affected joints, …

45 - 80 years of age All Phase N/A
S Stefano Zaffagnini, MD

Assessment of Periprosthetic Bone Mineral Density in Patients Undergoing Total Knee Prosthesis of Different Design

compare changes in BMD via DXA at the level of the femoral and tibial periprosthetic bone between two groups of patients undergoing cemented TKA of different design (posterior stabilization vs posterior cruciate preservation) with proms at a 2-year follow-up.

45 years of age All Phase N/A

Investigating the Role of Motivational Interviewing in Swedish Patients Undergoing Knee Arthroplasty

Knee arthroplasty is a successful surgical treatment for end-stage osteoarthritis. Most patients are satisfied with the result, however, 10% of the patients have remained dissatisfied over the last decades despite the advantages of the surgical procedure. Previous studies suggest that rehabilitation needs to be individualized and that some patients request …

years of age All Phase N/A

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