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knee-injuries Clinical Trials

A listing of knee-injuries medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 94 clinical trials
W Wafa Mohsin

SportsPro: Post-Market Clinical Follow Up Study

Retrospective, multi-center, chart review (only to include data that is part of the surgeons' standard practice)

18 years of age All Phase N/A
S Simone Gruber

JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

The goal of this observational study is to learn about the outcomes of medial patellofemoral ligament (MPFL) reconstruction for the treatment of recurrent patellar instability. The main questions it aims to answer are: What are the risk factors for recurrent patellar instability after MPFL reconstruction? What functional outcomes do patients …

10 - 35 years of age All Phase N/A
S Stefano Zaffagnini, MD

ACL Reconstruction: Clinical Outcome

The study is intended to include all patients who will undergo surgical reconstruction of the anterior cruciate ligament (ACL). The patients will be monitored and evaluated preoperatively and also at 6 months and 1, 2 and 5 years after the intervention through a clinical visit or telephone interview. Such assessments …

18 - 60 years of age All Phase N/A
C Colin Bond, PhD, MBA

Baseline ACL Injury Risk Screening and Normative Data

This is a prospective, observational cohort study aimed at establishing a database of normative biomechanics for healthy athletes and surveying these athletes for 12 months following baseline testing for the occurrence of new musculoskeletal injuries, with a particular emphasis on ACL injuries.

10 - 65 years of age All Phase N/A
L Lily M Waddell

Preventing Injured Knees From osteoArthritis: Severity Outcomes

This study is being done to find out if metformin is effective at reducing pain by delaying the onset of post-traumatic osteoarthritis (PTOA) after anterior cruciate ligament (ACL) reconstruction. This research study will compare metformin to placebo. The placebo tablet looks exactly like metformin, but contains no metformin. Placebos are …

18 - 45 years of age All Phase 2

Descriptive Study of Multiligamentary Reconstruction of the Knee

Evaluation of clinical results and postoperative laxity after single-stage reconstruction of multiligamentous lesions of the knee. Comparison of two types of transplant: allograft versus autograft. There is currently little data in the clinical outcome literature after allograft reconstruction. There is one study reporting postoperative laxity assessed by dynamic radiography in …

18 years of age All Phase N/A

Fixation of Patellar Tendon Grafts in Anterior Cruciate Ligament Reconstruction. Endobutton vs Metal Interference Screws

In this randomized controlled trial the investigators will compare the results after primary anterior cruciate ligament (ACL) reconstruction using two different methods for femoral fixation of a bone-patellar tendon-bone (BPTB) autograft. Interference screws have been the standard method for fixing the femoral side of BPTB grafts; however, several pitfalls have …

18 - 55 years of age All Phase N/A
B Becky Stone

Non- Vs Partial Controlled Weightbearing After Multiple Knee Ligament Reconstruction

This is a prospective randomized controlled trial with the purpose to determine if patients undergoing isolated posterior cruciate ligament (PCL) reconstruction, or isolated medial collateral ligament (MCL) reconstruction, or combined PCL, anterior cruciate ligament (ACL), fibular collateral ligament (FCL), posterolateral corner (PLC), and MCL reconstructions (or any combination of multiple …

14 - 59 years of age All Phase N/A
B Becky Stone

Full Vs Partial Weightbearing During the First Six Weeks of Rehab. After Fibular Collateral Ligament Reconstruction

This is a prospective randomized controlled trial with the purpose to determine if patients undergoing fibular collateral ligament (FCL) reconstruction alone or combined FCL and anterior cruciate ligament (ACL) reconstructions can safely begin full controlled weightbearing for the first six weeks after surgery.

14 - 59 years of age All Phase N/A

Establishing the Clinical Significance Values of the Lysholm Knee Score

The goal of this observational study is to learn about patients who will undergo anterior cruciate ligament reconstruction. The main questions it aims to answer are: What is the minimal clinically important difference value of the Lysholm Knee Score? What is the substantial clinical benefit value of the Lysholm Knee …

18 years of age All Phase N/A

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