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chemotherapy Clinical Trials

A listing of chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,618 clinical trials

Induction Toripalimab and Chemotherapy in Locally Advanced Cervical Cancer

To explore the efficacy of incorporating neoadjuvant immunotherapy into neoadjuvant chemotherapy in locally advanced cervical cancer patients with high risk of recurrence.

18 - 75 years of age Female Phase 1/2

Intrathecal Chemotherapy for Central Nervous System Metastasis in Retinoblastoma

Retinoblastoma is the most common intraocular malignancy in infancy and childhood. The overall survival rate of retinoblastoma was reported to exceed 95% when children were early diagnosed with localized intraocular phase. The advanced retinoblastoma cases with central nervous system metastasis (CNS)is associated with exceedingly poor prognosis. CNS metastasis is the …

years of age All Phase N/A
D Dr Joseph McCollom, DO

Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy

The purpose of this research study is to see how the brain changes in patients receiving chemotherapy (cytotoxic drug) treatment for colon or rectal cancer at Parkview Cancer Institute. This information will be used to identify helpful tests to diagnose individuals at risk for developing difficulties with thinking and memory …

18 years of age All Phase N/A
J Jennifer Ruth, RN, BSN

Pulsed Dose Chemotherapy Plus Pembrolizumab in Recurrent/Metastatic HNSCC

The rationale for the new sequence of pulsed dose chemotherapy proposed in this trial is based on the hypotheses that current standard dosing of chemotherapy plus pembrolizumab ultimately suppresses the immune system and has a negative effect on the efficacy of the anti-PD-1 monoclonal antibody (mAb) therapy and that chemotherapy …

18 years of age All Phase 2
I Ioannis Mantzaris, MD

Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDS

This is a Phase 1b, open-label study evaluating Venetoclax in combination with intensive induction and consolidation chemotherapy in previously untreated, adult patients with acute myeloid leukemia. In Part 1, the dose escalation phase, the safety and tolerability of the combination with Venetoclax at different doses and duration will inform the …

18 - 75 years of age All Phase 1
R Ryan Romasko

Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

This is an open-label, non-randomized, single-center, phase II study to evaluate the efficacy, toxicity and, tolerability of pre-specified dose attenuated chemotherapy regimens in lung cancer patients with comorbidities.

18 years of age All Phase 2
S Sohan L solanki, MD

An Audit of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Peritoneal carcinomatosis is a common event in the natural history of colorectal and other digestive tract cancers. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) provides a promising therapeutic option for highly selected patients with peritoneal carcinomatosis arising from different malignancies such as colorectal cancer, gastric cancer, ovarian cancer, or …

18 - 70 years of age All Phase N/A
I Irene Cantarero-Villanueva, PhD

Preventing Chemotherapy-induced Peripheral Neuropathy Using PRESIONA Exercise Program

The aim of this study is to determinate if therapeutic exercise with blood flow restriction (BFR) during neoadjuvant chemotherapy potentialy neurotoxic could prevent the onset of chemotherapy induced peripheral neuropathy (CIPN) comparing to usual care.

18 - 70 years of age Female Phase N/A
L Liren Qian, M.D.

CtDNA After Chemotherapy in Elderly Patients With Acute Leukemia

This study will monitor CtDNA After Chemotherapy in Elderly Patients With AL

60 - 100 years of age All Phase N/A

Alternate Day Fasting After Surgery for Patients Undergoing Chemotherapy

Endometrial cancer is the most common gynecologic cancer and ovarian cancer is the most lethal. The management of both advanced cancers is a combination of chemotherapy and surgery. Standard of care chemotherapeutic treatment for uterine and ovarian cancers is toxic and severely disruptive to the patient's quality of life with …

18 years of age Female Phase N/A

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