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chemotherapy Clinical Trials

A listing of chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,618 clinical trials
G Gerald Lim, MD

Chemoradiotherapy Versus Chemotherapy for Elderly and Frail GBM Patients

Currently, the optimal treatment regimen for elderly Glioblastoma (GBM) patients with poor performance status (PS) is unknown. Based on data for elderly GBM patients and the limited data for patients with poor PS, hypofractionated RT or a short course of Temozolomide (TMZ) may provide survival benefit without the added toxicity …

65 years of age All Phase 2
J Jiandong Zhang

Adebelizumab Combined With Chemotherapy and Radiotherapy Treat ES-SCLC

To observe the efficacy and safety of adebelizumab combined with chemotherapy and sequential adebelizumab combined with radiotherapy in the treatment of newly diagnosed extensive small cell lung cancer.

18 - 75 years of age All Phase 2

AI Prediction of Gastric Cancer Response to Neoadjuvant Chemotherapy

This study seeks to develop a deep-learning-based intelligent predictive model for the efficacy of neoadjuvant chemotherapy in gastric cancer patients. By utilizing the patients' CT imaging data, biopsy pathology images, and clinical information, the intelligent model will predict the post-neoadjuvant chemotherapy efficacy and prognosis, offering assistance in personalized treatment decisions …

18 years of age All Phase N/A
B Boormans

Chemotherapy and Sequential Immunotherapy for Locally Advanced Urothelial Cancer

Patients with locally advanced or clinically node positive urothelial carcinoma treated with chemotherapy, will receive 3 cycles of avelumab, followed by radical surgery.

18 years of age All Phase 2

Acupuncture for People Experiencing Period Loss Due to Chemotherapy

The purpose of this study is to find out whether it is practical (feasible) to use acupuncture to treat period loss (amenorrhea) caused by chemotherapy treatment in people with cancer. The researchers will look at how many participants enroll and complete the study. The researchers will also study how treatment …

15 - 40 years of age Female Phase 2
Y Yu Wang, M.D.

Induction IBI110 and Sintilimab with Chemotherapy in LA HNSCC

This study aims to investigate the efficacy and safety of combining sintilimab and the TP regimen with/without IBI110 for neoadjuvant chemotherapy in resectable locally advanced head and neck squamous cell carcinoma (HNSCC).

18 - 75 years of age All Phase 1/2
Z Zhijun Dai, Professor

Neoadjuvant Chemotherapy Combined With Toripalimab for TNBC (NEOTORCH-BREAST02)

This study is a prospective, single arm, multi-center phase II clinical trial. The primary study objective is to evaluate the pathologic complete response(PCR) of Adjuvant treatment of TNBC breast cancer with Toripalimab combined with neoadjuvant chemotherapy, including the incidences and types of adverse events. The secondary study objective is to …

18 - 70 years of age Female Phase 2
F Francesca Magnoni, MD

Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in IBC

This study will prospectively determine the feasibility and oncological safety of sentinel lymph node biopsy (SLNB) after neoadjuvant chemotherapy (NACT) in inflammatory breast cancer patients traditionally considered ineligible for SLNB due to locally advanced cancer with skin/chest wall involvement (cT4d) and heavy nodal burden at presentation (cN1/N2). This study will …

18 years of age Female Phase N/A
J Jin Jie

Blinatumomab Plus Reduced-dose Chemotherapy in Treating B-ALL

Precursor B cell acute lymphoblastic leukemia (B-ALL) is an aggressive type of leukemia, with high relapse rate and poor long term survival in adults. Traditional treatment regimens mainly include chemotherapy and hematopoietic stem cell transplantation. In the past decade, with the application of molecular targeted drugs and immunotherapy, the survival …

15 - 59 years of age All Phase 2
Y Yuan Ding, M.D.

Chemotherapy Combined with Immunotherapy and Targeted Therapy in Cholangiocarcinoma

This study aims to validate the efficacy and safety of GP/GEMOX combined with PD-1/L1 inhibitors and TKI agents in patients with advanced cholangiocarcinoma through a multicenter, retrospective study to guide clinical practice.

18 years of age All Phase N/A

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