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chemotherapy Clinical Trials

A listing of chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,618 clinical trials
T Theo Foukakis, MD, PhD

Use of GnRHa During Chemotherapy for Fertility Protection

Many cytotoxic drugs may harm the fertility of young women treated for cancer. The aim of the study is to investigate if the Gonadotropin-Releasing Hormone agonist (GnRHa) during cancer treatment can preserve the fertility of young female cancer subjects. Approximately 300 women with newly diagnosed breast cancer and up to …

14 - 42 years of age Female Phase 3
A Amparo Garcia-Tejedor, MDPhD

TAD After Chemotherapy in Locally Advanced Breast Cancer

This is an observational study to validate target axillary dissection (TAD) in locally advanced tumors (cN2 and/or cT4).

18 years of age All Phase N/A
A Aaron Riffa, BSN

Fostering Oral Chemotherapy Understanding and Safety (FOCUS) Study

The purpose of this study is to learn about the experiences of cancer patients during treatment utilizing a mobile app called EveryDose© to track prescribed oral treatment for cancer. Based on these experiences, the study team will decide on expanding this pilot study to evaluate other methods that may prove …

18 years of age All Phase N/A
A Ajay Goel, PhD

Prediction of Neoadjuvant Chemotherapy Response in Pancreatic Cancer

This study aims to develop and validate a predictive microRNA (miRNA) panel to assess the response to neoadjuvant chemotherapy (NACT) in patients with resectable and borderline resectable pancreatic ductal adenocarcinoma (PDAC).

18 years of age All Phase N/A
Y Yiwen Chen, MD

IBI343 Combined With Chemotherapy in Advanced Pancreatic Cancer

This study is a phase II study to evaluate the safety, tolerability and efficacy of IBI343 combined with chemotherapy in patients with advanced pancreatic cancer, including Part1 (safe lead-in phase) and Part2 (extension phase). In part1, patients with CLDN18.2-positive advanced pancreatic adenocarcinoma who had or had not previously received systemic …

18 years of age All Phase 2
J John G Lenehan, MD, FRCPC

CHemotherapy and Stool Transplant in PDAC (CHASe-PDAC)

To confirm the safety of combining oral fecal microbiota transplantation (FMT) with gemcitabine and nab-paclitaxel chemotherapy as first line treatment in patients with unresectable or metastatic pancreatic ductal adenocarcinoma.

18 years of age All Phase 1

Effectiveness of Pucotenlimab Combined With Standard Chemotherapy Regimen

This study comprises both Phase I and Phase II research. This phase focuses on safety, tolerability, and pharmacokinetics using a "3+3" dose escalation design with three dose groups: 1 mg/kg, 3 mg/kg, and 6 mg/kg. The drug will be administered in combination with the standard regimen for intermediate/high-risk rhabdomyosarcoma once …

1 - 18 years of age All Phase 1/2

Relapsed Follicular Lymphoma Randomised Trial Against Standard ChemoTherapy

The aim of the REFRACT clinical trial is to find new therapies with improved outcomes compared to the current standard treatment available, in patients with relapsed or refractory follicular lymphoma. This will be done by comparing patients who have received a new treatment against patients who receive standard treatment based …

18 years of age All Phase 2

Cognitive Impact of Neoadjuvant Chemotherapy for Ovarian Cancer

The purpose of this research is to assess several components of cognition in patients recently diagnosed with advanced epithelial ovarian cancer and who will be undergoing neoadjuvant chemotherapy for treatment of the cancer. 18 participants will be enrolled and can expect to be on study for approximately 10 months.

18 years of age Female Phase N/A

Holistic Acupuncture for Patients With Chemotherapy Induced Nausea

The study explores whether acupuncture as a supplement to conventional antiemetic medicine is superior in reducing the level of chemotherapy induced nausea compared to conventional anitemetic medicine alone. A total of 90 patients experiencing chemotherapy induced nausea will be allocated 1:1 to either acupuncture and antiemetic medicine or antiemetic medicine …

18 years of age All Phase N/A

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