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heart-failure Clinical Trials

A listing of heart-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 845 clinical trials
M Martin Schweiger, Prof, MD, MBA

Blood Based Assessment of sST2, Taken During and After Surgery, for Pediatric Patients With Heart Defects to Predict Heart Failure.

Patients younger than 18 scheduled for congenital heart surgery will be assessed during and post-operatively as well as at the first follow-up after 9-12 month for the novel biomarker sST2. We will assess the marker independently and in evaluation with other blood biomarkers to evaluate sings of heart failure. Compared …

- 18 years of age All Phase N/A
O Olga V. Tukish, Ph.D.

The Prevalence of Iron Deficiency and the Effectiveness of Ferinject® in Patients With HFpEF (ID-HFpEF)

Observational cohort randomized controlled study to study the influence of correction of ID by intravenous injection of ferric carboxymaltose (Ferinject®) on quality of life indicators, functional status in a cohort of patients with HFpEF.

18 years of age All Phase 4

CorWave LVAS FIH Study

The study is a prospective, multi-center, non-randomized trial to evaluate the safety and effectiveness of the CorWave LVAS for the treatment of advanced heart failure patients.

18 - 75 years of age All Phase N/A
B Brittany Meredith

DORAYA-HF Early Feasibility Study

The study objective is to evaluate the feasibility of the Doraya Catheter and measure clinical performance and safety endpoints, in ADHF patients deemed to have insufficient diuretic response.

18 years of age All Phase N/A

EACH-ADHF: Early Comprehensive Rehabilitation in Patients With ADHF

EACH-ADHF: Early Comprehensive Rehabilitation in patients with ADHF study is a multi-center, parallel-group, randomized controlled trial designed to evaluate the effects of the early comprehensive rehabilitation including exercise and inspiratory muscle training, over a period of 6 weeks, on the quality of life of patients with ADHF.

18 - 80 years of age All Phase N/A
A Amir Solomonica, MD

Safety and Performance Evaluation of the Nephronyx System for the Treatment of Patients With ADHF

The objective of this interventional study is to evaluate the safety and functional performance of the Nephronyx System in patients with ADHF, presenting clinical signs of volume overload and compromised response to diuretics.

18 years of age All Phase N/A

DORAYA-HF OUS Assessment of the Doraya Catheter for the Treatment of ADHF Patients With Insufficient Response to Diuretics

The study objective is to evaluate the feasibility of the Doraya Catheter and measure clinical performance and safety endpoints, in ADHF patients deemed to have insufficient diuretic response.

18 years of age All Phase N/A
A Ahmed M Kamal, Lecturer of Cardiovascular

The Effect of Dapagliflozin on Patients With Cardiomyopathy

This randomized controlled trial evaluates the efficacy and tolerability of early initiation of dapagliflozin in adult patients hospitalized with acute heart failure (AHF). The study aims to assess the effect of dapagliflozin on pulmonary congestion as measured by lung ultrasound (LUS), length of hospital stay, and cardiac and renal biomarkers. …

18 years of age All Phase 4
T Tamaz Shaburishvili, MD

Reprieve System Pilot Study

The objective of the study is to evaluate the use of the Reprieve System to decongest subjects with acute decompensated heart failure.

18 years of age All Phase N/A
P Philippe MENASCHE, MD, PhD

Treatment of Non-ischemic Cardiomyopathies by Intravenous Extracellular Vesicles of Cardiovascular Progenitor Cells

The goal of this clinical trial is to assess the safety and efficacy of three intravenous injections of the extracellulat vesicle-enriched secretome of cardiovascular progenitor cells in severely symptomatic patients with drug-refractory left ventricular (LV) dysfunction secondary to non-ischemic dilated cardiomyopathy. The main questions it aims to answer are: Are …

18 - 80 years of age All Phase 1

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