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heart-failure Clinical Trials

A listing of heart-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,033 clinical trials
M Morten Bøttcher, MD, PhD

Exogenous KETOne Supplements in Patients Hospitalized for Acute Heart Failure

This is a multicenter, randomized, double-blind, placebo-controlled trial to investigate the clinical efficacy of treatment with exogenous dietary ketone supplement containing 1,3-butanediol in patients hospitalized with acute heart failure (AHF), potentially leading to better clinical outcomes.

18 - 100 years of age Both Phase 2
M Mina Fam, Resident

Stellate Ganglion Block as Novel Treatment for Heart Failure Patients

Stellate Ganglion Block as Novel Treatment for Heart Failure Patients

18 - 70 years of age Both Phase 2/3

Coronary Sinus Reducer For The Management Of Symptomatic Heart Failure

The purpose of this study is to evaluate the efficacy of CS Reducer implantation in patients with HFpEF and CMD on left ventricular filling pressures, specifically invasive measurement of PAWP during standardized exercise.

18 - 100 years of age Both Phase N/A
M Marcus Dörr, MD

Cardiovascular Effects of Preferred Home-based Exercise Training in Systolic Heart Failure

The aim of the study is I. To assess whether an individualized exercise training program is superior as compared to usual care with respect to exercise tolerance, II. to assess whether intervention tools that aim to increase exercise adherence are superior to an individualized exercise training alone with respect to …

30 - 75 years of age Both Phase 3
D Daniel Xu

Empagliflozin for New On-set Heart Failure Study Regardless of Ejection Fraction

Heart failure (HF) is one of the most important reasons for hospital admission and is associated with high mortality and morbidity. After discharge, up to 40% of patients are readmitted within 6 months and 1-year post-discharge mortality is high. The cost burden of treating patients with HF is high and …

18 - 100 years of age Both Phase 3
H Helene Brown, RN. B.Sc.

Patient SELF-management With HemodynamIc Monitoring: Virtual Heart Failure Clinic and Outcomes

To demonstrate that a virtual Heart Failure Clinic (HFC) based on patient self-management using Pulmonary Artery Pressure (PAP) monitoring is superior to usual care of HFC, leads to decreased: hospital admissions for heart failure (HF), emergency department consultation and/or unplanned intravenous heart failure therapy and cardiovascular death, compared to a …

18 - 100 years of age Both Phase N/A
I Inne P Farissa, MD

Combination Oral Acetazolamide and Intravenous Furosemide on Acute Decompensated Heart Failure Outcomes

Based on ADVOR trial, the potential of adding acetazolamide in increasing the success of decongestion, the amount of natriuresis and diuresis. However, the use of intravenous acetazolamide may not be possible in Indonesia, where the intravenous formulation is not available. This clinical research study is being conducted in single hospitals …

18 - 100 years of age Both Phase 4
N Nguyen Dang P Kieu, M.D.

The Effect of Resistance Training on Sarcopenia in Older Heart Failure Patients

The goal of study is to evaluate the effects of an eight-week machine-based resistance training program on managing sarcopenia in older outpatients with chronic heart failure (HF) at Military Hospital 175.

60 - 100 years of age Both Phase N/A
E Emil Wolsk, MD

Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy

New onset heart failure (HF) is observed in up to 25% of patients with incident atrial fibrillation or flutter (AF). Current guidelines suggest that both conditions (AF & HF) be addressed with guideline directed medical therapy (GDMT) for HF and rate or rhythm control of AF. Hence, patients with both …

18 - 100 years of age Both Phase 2/3
E Emily Guy, B.S

PRIME HFrEF: Novel Exercise for Older Patients With Heart Failure With Reduced Ejection Fraction

This study is trying to find out whether performing a hybrid aerobic-resistance exercise training program (titled PRIME: Peripheral Remodeling via Intermittent Muscular Exercise) results in better health outcomes than the traditional exercise training program (called COMBO) that is used in individuals with heart failure with reduced ejection fraction (HFrEF). Participants …

65 - 100 years of age Both Phase N/A

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