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heart-failure Clinical Trials

A listing of heart-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 840 clinical trials
C Cindy Hall

A Feasibility Study Implant of the WiSE® CRT System With an Intracardiac Pacemaker to Achieve Totally Leadless CRT

Assess the safety and efficacy of the co-implantation of the WiSE CRT System with an intracardiac pacemaker to provide totally leadless CRT.

22 years of age All Phase N/A
G Giovanni Luca Botto, MD

heaRtInsiGHT Alert guIDE: RightAIDE Application of the HeartInsight Acute Heart Failure Predictor in Routine Clinical Practice: Organizational Models and Workflow.

The RightAIDE study is a prospective, multicenter, observational registry designed to evaluate the real-world application of the HeartInsight™ algorithm for predicting acute heart failure (HF) events in patients implanted with a Biotronik ICD or CRT-D device with atrial sensing and Home Monitoring capability. Heart failure is a growing public health …

18 years of age All Phase N/A
M Mansoura University Hospital

Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF

This study looks at people with heart failure who are admitted to the hospital. The goal of the study is to understand whether taking a heart failure medicine called angiotensin receptor-neprilysin inhibitor (ARNI) before hospital admission affects short-term health outcomes. The study will compare two groups of participants: those who …

18 years of age All Phase N/A
R Ruwanthi J Perera

The WiSE®-UP Registry (The WiSE System Utilization & Performance Registry)

Observe to understand product performance, including patient safety, clinical outcomes, and CRT response information associated with the use of the market-released WiSE System

years of age All Phase N/A
S Stefano Ghio, PI

Registry of Pavia Chronic Heart Failure Patients-observational Study

Registry of Pavia chronic heart failure patients-observational study

18 years of age All Phase N/A
M Manisha Bajpai, PhD

The Salt Study for Heart Failure

The purpose of this study is to understand if low sodium (cardiac) diet is indeed necessary for better health outcomes in patients who suffered heart failure. This study will investigate the association between sodium intake and risk for 30-day re-admission in Heart Failure (HF) patients.

18 years of age All Phase N/A
L Lucas C Petersen

Medication Withdrawal in Stable HF With Improved LVEF

The goal of this clinical trial is to evaluate the safety and feasibility of withdrawing mineralocorticoid antagonists (MRA) in patients with stable heart failure with improved left ventricular ejection fraction (HFimpEF). The main questions it aims to answer are: Does withdrawal of MRAs lead to a reduction in left ventricular …

18 years of age All Phase 2/3
J Joseph Cheriyan, MBChB MA FRCP FESC FACC

Utilising AI Analysis of Sounds To prEdict heaRt failurE decOmpensation

This is an open-lable, multicenter Phase II study to evaluate the safety, tolerability, and efficacy of IBI363 in advanced melanoma patients

18 years of age All Phase N/A
N Nuria Farre, MD, PhD

Heart Failure Virtual Ward Research Study

The main aim will be to evaluate whether a follow-up with virtual wards reduces HF hospitalisation at three months follow-up. Hospital admission will be defined as any hospital admission, or an emergency room stay of more than 24 h requiring IV diuretics. The secondary objectives will be to evaluate whether …

18 years of age All Phase N/A
E Elaine Franko

Fluid Guided Heart Failure Treatment at the Cleveland Clinic

FIGHT-HF is an exploratory non-randomized open-label study evaluating a heart failure management intervention. The goal of this pilot is to assess the performance of a fluid-guided heart failure management program and Alert Response Guide (ARG) using the Bodyport Cardiac Scale and Congestion Index in 50 adult participants with acute and …

21 years of age All Phase N/A

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