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heart-failure Clinical Trials

A listing of heart-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 844 clinical trials
B Baldeep Sidhu, MD

Monitoring Oedema in Heart Failure to Improve Function and Reduce Hospitalisation Risk

This study will evaluate the Heartfelt device, a novel, passive monitoring system that detects early signs of fluid build-up in patients (oedema) with heart failure by measuring changes in foot and lower leg volume through capture of 3D images. The trial will assess whether this device, when added to standard …

18 years of age All Phase N/A

Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation

The goal of this clinical trial is to evaluate the effects of a home-based exercise program using mobile technology on physical activity and capacity, frailty and muscle mass, and quality of life in patients with a newly implanted HeartMate 3 left ventricular assist device (HM3 LVAD). Researchers will compare the …

18 years of age All Phase N/A

Effectiveness of a Cardiac Telerehabilitation Program in Chronic Heart Failure

The goal of this observational study is to evaluate whether a home-based cardiac tele-rehabilitation program can improve functional capacity in adults (18 years and older) with chronic heart failure. The main questions it aims to answer are: Does tele-rehabilitation improve peak oxygen uptake (VO₂ max) compared to standard in-hospital rehabilitation? …

18 years of age All Phase N/A
R Rita Queirós

PRIMARY-HF: Heart Failure Screening in Primary Care Using Point-of- Care

The goal of this clinical trial is to evaluate whether the use of NT-proBNP testing and point-of-care ultrasound (POCUS) can improve the diagnosis and management of heart failure in adults aged 50 years or older with suspected heart failure or cardiovascular risk factors in primary care settings. The main questions …

49 years of age All Phase N/A
A Anna Maria Scandroglio, MD

Evaluating Adherence to Guideline-Directed Medical Therapy in Patients With Advanced Heart Failure

A Prospective Observational, Multi-Center, Real-World Pharmacological Study Evaluating Adherence to Guideline-Directed Medical Therapy Using the Four-Pillar Strategy in Patients with Advanced Heart Failure

18 - 75 years of age All Phase N/A
V Valesha Province, MS

Wearable Technology in Heart Failure Patients

The primary objective is to establish a Cleveland Clinic-led registry designed to integrate continuous physiological data from consumer wearables, captured by the HeartBit app and a Case Western Reserve University (CWRU)-based platform, with clinical data from patients' individual Electronic Health Record (EHR). This proposal is for understanding the use of …

18 - 85 years of age All Phase N/A

the Clinical Outcome of Empagliflozin in Pediatric Heart Failure Patients

the study to investigate the efficacy of empagiflozin in pediatric heart failure

1 - 18 years of age All Phase 2
S Samuel S Mutasingwa, MD

Sacubitril-valsartan in Patients With Heart Failure With Reduced Ejection Fraction From Rural Tanzania

Angiotensin-neprilysin inhibitors (ARNI) are beneficial in patients with heart failure with reduced ejection fraction. No study evaluating ARNI has been conducted in sub-Saharan Africa (except South Africa) yet, where heart failure is a major health problem. Before implementing ARNI in Tanzania, a study evaluating the benefit and safety of ARNI …

18 years of age All Phase 4
X Xuening Li

A Clinical Study of HRS-7156 in Healthy Participants

The purpose of this Phase I study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HRS-7156 in healthy participants.

18 - 55 years of age All Phase 1
R Rengin Demir, Prof. Dr.

Investigation of the Effect of Inspiratory Muscle Training and Dual-Task Inspiratory Muscle Training on Cognitive Functions in Heart Failure

The goal of this clinical trial is to evaluate whether dual-task inspiratory muscle training (IMT) is effective in improving cognitive and functional outcomes in adults with heart failure. It will also assess the effects of standard IMT and compare both approaches. The main questions it aims to answer are: Does …

40 years of age All Phase N/A

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