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heart-failure Clinical Trials

A listing of heart-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 840 clinical trials
N Nils Daum

Intensive Care Unit-acquired Heart Failure in Critically Ill: the ICU-HF Study

Critically ill patients in intensive care units (ICUs) are exposed to a wide range of complications that can affect long-term morbidity and mortality. Not only the initial diagnosis at the time of admission may lead to complications; the ICU stay itself can also be associated with specific disease patterns. One …

18 years of age All Phase N/A
J Johan Sundström

Uppsala Self-SCREENing of Heart Failure Study

The goal of this clinical trial is to investigate whether a stepwise multimodal home-based screening strategy with rapid point-of-care testing can detect undiagnosed heart failure (HF) in high-risk patients compared to usual care. The study also aims to understand the impact of earlier HF diagnosis on treatment initiation, clinical outcomes, …

40 years of age All Phase N/A
N Naoko Perkiö Kato, RN, PhD

Effect of Non-Invasive Lung Fluid Monitoring for Heart Failure Management in Primary Care

Remote dielectric sensing (ReDS) technology offers a non-invasive method for assessing lung congestion. This randomized controlled trial aims to evaluate the effectiveness and processes of the ReDS-guided heart failure management program in primary care settings for patients with heart failure.

18 years of age All Phase N/A

Clonal Hematopoiesis of Indeterminate Potential in Heart Failure.

Study will be directed to evaluate the dentoalveolar changes following maxillary incisor intrusion using utility arch assisted with micro-osteoperforations in deep bite cases.

18 years of age All Phase N/A

The PURI-HF (Air Purifiers on Heart Failure) Trial

Indoor air pollution and fine mode particulate matter with an aerodynamic diameter smaller than 2.5 micrometers (PM2.5) is a major contributor to global morbidity and mortality, particularly due to cardiovascular disease. This project aims to demonstrate the efficacy, feasibility and effectiveness of portable air filters in improving indoor PM2.5 levels …

18 years of age All Phase N/A

Reduction of Mitral Regurgitation With the SATURN Trans-Septal Transcatheter Mitral Valve Replacement (TMVR) System in Patients With Severe Symptomatic Mitral Regurgitation

The goal of this clinical trial is to evaluate feasibility, safety, and performance of the SATURN TS TMVR System for the treatment of moderate-to-severe or severe, symptomatic mitral regurgitation through a transcatheter approach. The main questions it aims to answer are: is the use of the device feasible? is it …

65 years of age All Phase N/A

SGLT2 for Heart Failure in CHD Patients

Heart failure (HF) in adult patients with congenital heart disease is a major cause of morbidity and mortality. Approximately 30% of patients with significant congenital heart disease will develop signs of heart failure. Heart failure leads to hospitalization and disability with a longer hospital stay and higher health care costs …

18 years of age All Phase N/A
F Francisco José Pastor Pérez

Compression Therapy of the Lower Limbs in Patients With Decompensated Heart Failure

Randomized 1:1 multicenter double-blind clinical investigation evaluating the efficacy and safety of compression therapy of the lower limbs plus parenteral administration of diuretics vs. administration of parenteral diuretics alone (standard treatment) in patients with decompensated HF and predominantly systemic tissue congestion and absence of intravascular systemic congestion. Patients will be …

18 years of age All Phase N/A
C Carlo Pappone, MD, PhD

Acute Response to Left Bundle Branch Area Pacing With SyncAV

This clinical investigation is a prospective, single-arm, post-market, non-randomized, single-center study designed to evaluate the effectiveness of the SyncAV CRT dynamic atrioventricular (AV) delay feature when used with left bundle branch area pacing (LBBAP).

18 years of age All Phase N/A
A Ambarish Pandey, MD

Home-based Cardiac Rehabilitation in Heart Failure

This study evaluates a mobile health (mHealth) home-based cardiac rehabilitation program for patients with heart failure. We will stratify randomization between rural and urban populations, with the goal to assess implementation of cardiac rehabilitation across these two geographic areas. . The study will randomize 332 patients with heart failure (ejection …

18 years of age All Phase 3

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