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heart-failure Clinical Trials

A listing of heart-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 844 clinical trials
N Nir Ayalon, Dr.

A Multi-center, National, Open-label, Prospective Study to Evaluate the Performance of the V-Lap™ System

The goal of this clinical trial is to learn about the safety of a single dose of HB-2121 in adults with suspected celiac disease. It will also look at how the drug affects the small intestine. The main questions it aims to answer are: What side effects do participants have …

22 - 88 years of age All Phase N/A
B Bastian Schmack, PD

The "Seamless" Patient:From Preoperative Preparation to Postoperative Rehabilitation

The "seamless" patient: from preoperative preparation to postoperative rehabilitation. The effects of digital services for perioperative care of patients undergoing cardiac surgery will be investigated

18 years of age All Phase N/A
A Alessia Martina Trenta, Dr

The Effects of Body Scan on Enteroception in Patients With Heart Failure

The study aims to explore the effects of body scan on enteroception in people with heart failure

18 - 75 years of age All Phase N/A
M Malene Hammer

Home-based Cardiac Rehabilitation for People Living With Heart Failure and Their Caregivers- The DK:REACH-HF Pilot Study

Background: Participation in cardiac rehabilitation (CR) is a strong recommendation of clinical guidelines for the management of heart failure (HF) because it is demonstrated to be a clinically effective and cost-effective intervention. Despite this, Danish data shows the uptake of CR is suboptimal (51%). A major barrier is that the …

18 years of age All Phase N/A
D Daniele Masarone Dr.

CCM and Implementation of Guideline-Directed Medical Therapy in Patients With Heart Failure (Fix-GDMT-HF)

The primary objective of this study is to evaluate the impact of Cardiac Contractility Modulation (CCM) therapy on the initiation and up-titration of Guideline-Directed Medical Therapy (GDMT) in patients with heart failure (HF). This will be assessed by the change in Quad Medication Score (QMS) from baseline (pre-CCM) to 6-month …

18 years of age All Phase N/A
M Maurizio Volterrani, Professor

Drug Management in Heart Failure

Aim of the proposal is to create an interactive AI-based multicentre prospective database to provide information on how to improve the QoC for pts with HF.This will provide detailed information on pts characteristics,treatment practices, adherence to prescribed guideline-based optimal drug therapy,and outcomes.The database stems from a registry started two years …

18 years of age All Phase N/A
W William Beaubien-Souligny, MD PhD

A Portable Thoracic Impedance Device for Detecting Pulmonary Congestion in Heart Failure Patients

This study investigates a portable thoracic bioimpedance tomography (TBIT) device designed to detect early lung congestion in heart failure patients. The main goal is to evaluate how well the device's measurements match those obtained from lung ultrasound and other imaging techniques. By detecting lung fluid build-up before symptoms worsen, this …

18 years of age All Phase N/A
A Andrew Flett

IRONHEART: Intravenous Iron in Non-ischaemic Heart Failure

The aim of this study is to observe the effect of intravenous ferric derisomaltose in participants with non-ischaemic heart failure (LVEF\<40%), iron deficiency (TSATS\<20%) and established on heart failure therapy including Sodium-glucose cotransporter 2 inhibitors (SGLT2i). Participants will undergo baseline laboratory blood tests, cardiac magnetic resonance imaging (cMRI), six-minute walk …

18 years of age All Phase N/A
R Rossella Cianci

Genetic and Immunity in Heart Failure

Heart failure is a major health problem with serious consequences on mortality and morbidity worldwide. In chronic heart failure an alteration of the inflammatory state occur. The aim of this study will be to describe the relationship between markers of inflammation in patients with heart failure with preserved ejection fraction, …

18 years of age All Phase N/A

Inspiratory Muscle Training in HFpEF

This study is being done to determine how inspiratory muscle training impacts inspiratory muscle function during exercise in heart failure patients.

18 years of age All Phase N/A

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