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heart-failure Clinical Trials

A listing of heart-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 851 clinical trials
J Juan Carlos López-Azor, PhD

Multidimensional Impact of Telemonitoring in Heart Failure (IMPACT-HF)

The goal of this clinical trial is to know if telemonitoring and telematic follow-up reduces the healthcare resources utilization, healthcare costs and non-healthcare costs of patients with high-risk heart failure. The main questions it aims to answer are: Does telematic follow-up reduce de use of healthcare resource utilization of patients …

18 years of age All Phase N/A
M Marat Fudim

Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection Fraction

Heart failure (HF) affects more than 6 million adults in the U.S. alone, with increasing prevalence. Cardiovascular congestion with resultant limitation in physical activity is the hallmark of chronic and decompensated HF. The current HF physiologic model suggests that congestion is the result of volume retention and, therefore, therapies (such …

18 years of age All Phase N/A

Impact of a Physical Exercise Program on the Self-care Capacity of People Hospitalized for Heart Failure

The objective of the study is to evaluate the effectiveness of a self-care program that integrates physical exercise with components of aerobic and muscular strength training in improving functional capacity and muscular strength in people hospitalized for decompensated heart failure, in a clinical stabilization phase The main question it aims …

18 years of age All Phase N/A
F Francesco Papalia

Randomised Controlled Trial for Assessing the Effectiveness of an Inclusive Heart Failure Monitoring and TRACKing Solution in the UK.

The objective of our research is to evaluate the effectiveness of an innovative medical device designed to measure foot and lower leg sizes in detecting early indications of deteriorating heart failure. This health condition frequently causes leg swelling and breathing difficulties due to fluid accumulation. Early detection of these symptoms …

18 years of age All Phase N/A
H Haibo Chen

Corheart 6: Long-term Cohort Study

This study aims to evaluate the long-term effectiveness and safety of Corheart 6 left ventricular assist system as a treatment for patients with advanced left heart failure. The patients who have received the Corheart 6 treatment since October 2021, or who are planned to received it, will be enrolled until …

18 years of age All Phase N/A
M Marco Montomoli

Effect of the Use of Dapagliflozin in Patients With Refractory Heart Failure

Cross-over, 2-sequence, 2-treatment, 2-period single-centre, phase IV, randomized, open label study.

18 years of age All Phase 4

Nurse-led Education on Patients With Chronic Heart Failure and Their Informal Caregivers

The current study intends to examine the influence of nurse-led education on patients with chronic heart failure and their caregivers, with the goal of optimizing care for both and improving patients' clinical outcomes.

18 years of age All Phase N/A
D Diana A Gorog

Safety of AI-Powered Virtual Assistant in Outpatient Management of Heart Failure

The aim of this pilot randomized study is to examine whether integrating the SIRIO-HF virtual assistant (VA) into the outpatient management of participants recently discharged from hospital with a new diagnosis of heart failure (HF), may reduce the need for regular medical assessment and the healthcare burden, reduce variability in …

18 years of age All Phase N/A
A Almagul Kushugulova

The Gut Microbiome in Chronic Heart Failure

there are numerous studies, most of which are predominantly associative in nature, investigating the association between the gut microbiota and various pathologies. However, to establish a causal relationship between microbiome composition and chronic heart failure (HF), clinical studies are needed, particularly using probiotics that can modify the composition and function …

18 years of age All Phase N/A

HOPE At Heart (HOPE) of Donor Hearts After Circulatory Death (DCD) Using the XVIVO Heart Assist Transport System.

The purpose of the clinical investigation is to support the use of direct procurement of donor hearts in donation after circulatory death followed by hypothermic oxygenated perfusion using the XVIVO Heart Assist Transport System. Thereby increasing the utilization of DCD donor hearts in donation after circulatory death. The primary objective …

18 years of age All Phase N/A

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