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heart-failure Clinical Trials

A listing of heart-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 845 clinical trials
B Brian Chan, MD, MPH

Rural Community Peer Partnerships for Improving Methamphetamine-Associated Heart Failure Screening and Engagement

The goal of PEER-Heart is to implement and assess feasibility and preliminary effectiveness of a community peer-facilitated screening for methamphetamine-associated heart failure (MAHF) and linkage to evidence-based cardiology care for people who use methamphetamine in rural areas.

18 years of age All Phase N/A

Reduction of Mitral Regurgitation With the SATURN Trans-Septal Transcatheter Mitral Valve Replacement (TMVR) System in Patients With Severe Symptomatic Mitral Regurgitation

The goal of this clinical trial is to evaluate feasibility, safety, and performance of the SATURN TS TMVR System for the treatment of moderate-to-severe or severe, symptomatic mitral regurgitation through a transcatheter approach. The main questions it aims to answer are: is the use of the device feasible? is it …

65 years of age All Phase N/A
J Julio Nunez Villota, MD

Compression Therapy of the Lower Limbs in Patients With Decompensated Heart Failure

Randomized 1:1 multicenter double-blind clinical investigation evaluating the efficacy and safety of compression therapy of the lower limbs plus parenteral administration of diuretics vs. administration of parenteral diuretics alone (standard treatment) in patients with decompensated HF and predominantly systemic tissue congestion and absence of intravascular systemic congestion. Patients will be …

18 years of age All Phase N/A
H Haibo Chen

Corheart 6: Long-term Cohort Study

This study aims to evaluate the long-term effectiveness and safety of Corheart 6 left ventricular assist system as a treatment for patients with advanced left heart failure. The patients who have received the Corheart 6 treatment since October 2021, or who are planned to received it, will be enrolled until …

18 years of age All Phase N/A
M Marco Montomoli

Effect of the Use of Dapagliflozin in Patients With Refractory Heart Failure

Cross-over, 2-sequence, 2-treatment, 2-period single-centre, phase IV, randomized, open label study.

18 years of age All Phase 4
L Li Xuping, PhD

Comparison of Catheter Plus Marshall Vein Ablation vs. Catheter Ablation Alone in Persistent AF With Heart Failure

This multicenter, randomized controlled trial aims to compare the clinical efficacy and safety of combining catheter ablation with Marshall vein ethanol ablation versus catheter ablation alone in patients with persistent atrial fibrillation (AF) and concomitant heart failure. Persistent AF is a common arrhythmia that significantly impacts the quality of life …

18 - 80 years of age All Phase N/A
S Sachin Vispute, MPH, MSEd

iCardia4HF: Multi-component mHealth Intervention for Patients With Heart Failure

The goal of this factorial randomized trial is to examine the independent and synergistic efficacies of two mobile health technology interventions in people with chronic heart failure. The first intervention involves the use of multiple consumer mHealth apps and sensor devices (MyApps) for heart failure self-care (maintenance, monitoring, and management). …

18 years of age All Phase 2/3

Mechanisms of Diuretic Resistance in Heart Failure, Aim 3

Randomized double-blind placebo-controlled crossover study design

18 years of age All Phase 1
M Markus Wallner, MD

Efficacy of an Assisted Therapy Optimizing Module to Improve Physician Adherence

Heart failure patients within the HM programme

18 years of age All Phase N/A
T Terjei Øvrebotten, MD

Management of Patients with Heart Failure At Home After Hospital Discharge

This study aims to assess whether patients with acute heart failure (HF) can achieve the same level of HF-therapies by digital follow-up at home as compared to hospital visits according to the STRONG-HF strategy. Patients admitted to hospital with acute HF will be enrolled and randomized to either follow-up at …

18 - 85 years of age All Phase N/A

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