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Osteoarthritis Clinical Trials

A listing of Osteoarthritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 536 clinical trials
P Peter den Hollander, MD

RSA-RCT: Attune S+ TKA Versus Sigma TKA

The PFC Sigma Knee by DePuy Synthes is an excellent knee replacement with an excellent clinical track record, good survival rates (98% 10 years survival in patients aged \< 55 years) and minimal early migration as measured with RSA (0.5mm MTPM at two years follow-up). The Attune Knee by DePuy …

21 - 90 years of age All Phase N/A
M Martin Gesheff

The Pericapsular Nerve Block in Total Hip Arthroplasty

In order to continue progressing towards outpatient total hip arthroplasty (THA), methods to adequately manage postoperative pain is of paramount importance. The purpose of this study is to quantify the effectiveness of the pericapsular nerve block in total hip arthroplasty in comparison to the fascia iliaca nerve block.

18 - 80 years of age All Phase 4
m meixuan Zhu

Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA

This study will combine brain imaging and neuromodulation tools to investigate the underlying neurobiological mechanisms of exercises. The findings will enhance our understanding of the mechanisms underlying mind-body exercise and facilitate the development of new pain management approaches.

45 - 75 years of age All Phase 2

The PROACTIVE Study for Black Elders

Chronic musculoskeletal pain (CMP), while a leading cause of physical disablement, is a neglected national health disparity issue in Black communities. The purpose of this study is to test a novel culturally congruent pain self-management intervention. A total of 120 persons aged 50-92, self-identifying as Black or African American having …

50 - 92 years of age All Phase N/A
M Malgorzata Reysner, M.D. Ph.D.

PENG Block With Dexmedetomidine in Older Adults

Pain after hip surgery is a common problem in older adults and may delay early mobilization, increase the need for opioid pain medications, and contribute to complications such as delirium, nausea, or prolonged hospital stay. Regional anesthesia techniques are increasingly used to improve pain control while reducing the use of …

65 - 100 years of age All Phase N/A
G Gilvan F Vaz, MD

Continuous Radiofrequency in Hip Osteoarthritis Pain: A Randomized Clinical Trial.

This will be a prospective, single-center, double-blinded, randomized study designed to compare the efficacy of the intraarticular injection of a corticosteroid and the Conventional Radiofrequency (CRF) of the anterior sensory branches to the hip in controlling pain and improving function related to hip osteoarthritis.

18 years of age All Phase N/A
D Dana Farrell, BS,PMP

Influence of Antiseptic Washes on Wound Healing Complications After THA

The purpose of this research trial is to evaluate the effect of two types of washing solutions on wound healing after total hip replacement surgery. Washing solutions are used routinely during total hip replacements to clean the wound after the components have been placed and the wound is about to …

18 years of age All Phase N/A
P Paul Maisongrosse

Multicentre SMS Study - FR

Prospective, multicentre, non controled, non randomised, clinical study to assess the performance and the stability of SMS femoral stem

18 - 85 years of age All Phase N/A
M Malgorzata Reysner, M.D. Ph.D.

PENG Block Variants With Dexamethasone and Dexmedetomidine in Older Adults

This study will compare three different versions of the Pericapsular Nerve Group (PENG) block in adults aged 65 years and older who are undergoing surgery for hip conditions. The PENG block is a regional anesthesia technique that can reduce pain after surgery and decrease the need for strong opioid pain …

65 - 100 years of age All Phase N/A
A Anna Vasara, MD, PhD

Complex Molecular Etiology and Cellular Landscape of Hip Osteoarthritis

The purpose of this study is to cast light on the highly complex etiology and cellular landscape of hip osteoarthritis by utilising single-cell and spatial omics.

18 - 74 years of age All Phase N/A

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