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Osteoarthritis Clinical Trials

A listing of Osteoarthritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 536 clinical trials
M Malgorzata Reysner, M.D. Ph.D.

PENG Block vs Suprainguinal FICB vs Lumbar ESPB for Analgesia After Hip Surgery

This randomized, double-blinded, controlled clinical trial compares three motor-sparing regional anesthesia techniques used for postoperative analgesia in patients undergoing hip arthroplasty: the Pericapsular Nerve Group (PENG) block, the suprainguinal Fascia Iliaca Compartment Block (S-FICB), and the Lumbar Erector Spinae Plane Block (L-ESPB). Although all three techniques are widely used in …

65 - 100 years of age All Phase N/A
M Malgorzata Reysner, M.D. Ph.D.

Three Variants of the PENG Block With and Without Perineural Adjuvants in Older Adults

This study will compare three versions of the Pericapsular Nerve Group (PENG) block in adults aged 65 years and older who are undergoing hip surgery. The PENG block is a regional anesthesia technique used to reduce pain around the hip joint and may improve early recovery after surgery. All patients …

65 - 100 years of age All Phase N/A
A Amelia Millward

Live and Interactive Fitness Training Program (Vivo Knee OA)

Potential participants will be screened at clinic. Patients who meet eligibility criteria will be considered for study. After written informed consent is obtained, participants will complete baseline testing and participants who meet eligibility criteria will be randomized 1:1 to 2 treatment arms: Vivo Arm: Vivo twice a week for 6 …

55 - 85 years of age All Phase N/A
D Diederik de Boer, MSc.

Direct Superior Approach Versus PosteroLateral Approach in Total Hip Arthroplasty (SPLAsH)

This study will compare postoperative pain, health related quality of life (HRQoL), function, rehabilitation, urinary incontinence, muscle atrophy and component positioning in total hip arthroplasty (THA) using the posterolateral approach (PLA) or the direct superior approach (DSA). In addition, the CT images will be used to validate a new metal …

18 - 99 years of age All Phase N/A
P Pang-Hsin Hsieh, MD

Comparison of Clinical Results of Two Cementless Femoral Stem

In the present study, two types of cementless femoral stem- UTS Stem and UTF-reduced Stem- were utilized in total hip arthroplasty. Due to the design for proximal femur fixation, both femoral stems could prevent stress shielding around the implant, further preventing osteolysis. The difference between both femoral stems is the …

20 years of age All Phase N/A
N Nicola Baldini, M.D.

Study of Parameters of Osteosarcopenia in Patients With Hip Fracture

The study aims to assess the adequacy of a set of clinical and laboratory investigations for identifying the osteosarcopenia status in patients undergoing a hip replacement for a fragility fracture of the femoral neck. The control group will consist of patients undergoing a hip replacement for osteoarthritis, as the decrease …

65 years of age All Phase N/A
Y Yukio Nakamura, MD, PhD

Non-weight Bearing in Hip Joint With Accompanying Joint Pain Might Not Progress Radiographic OA

As we have previously reported, the primary cause of hip OA with accompanying joint pain might be bone alterations which can be microfracture. In order to prove it, it is planned that conservative treatment will be performed on the hip OA patients with accompanying joint pain for the first year. …

years of age All Phase N/A

6-month Efficacy and Safety of Synolis VA 80/160 in Hip Osteoarthritis

Multicenter, independent study of Synolis VA 80/160 over a period of 6 months

18 years of age All Phase N/A
M Miguel Jaramillo

Gait After THA: Direct Anterior vs Manual Posterior vs Robotic Posterior

The purpose of this study is to evaluate the gait biomechanics following THA on 3 groups of subjects undergoing DAA (manual) and PA (manual and robotic) surgical approaches.

18 years of age All Phase N/A

PENG Block & PENG PRF

The primary aim of this study is to prospectively compare the effects of the pericapsular nerve group (PENG) block alone and the combination of PENG block with pulsed radiofrequency (PRF) on pain intensity in patients with chronic hip pain. As a secondary aim, the effects of both treatment modalities on …

18 - 80 years of age All Phase N/A

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