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Osteoarthritis Clinical Trials

A listing of Osteoarthritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 515 clinical trials
K Katie Boncella

Knee Osteoarthritis Rehabilitation Through Rotational Inertia

This study is testing whether a new type of exercise program, called eccentric overload training using a flywheel device, can improve stair-climbing ability in people with knee osteoarthritis. The flywheel device provides resistance throughout the entire movement and gives extra challenge during the muscle-lengthening phase of exercise. This type of …

40 - 70 years of age All Phase N/A
S Sherwood Alexis, MHA, MBA

Remote Tai Chi for Knee Osteoarthritis

The goal of this pragmatic randomized trial is to evaluate the effectiveness of remote Tai Chi to treat knee pain in adults with knee osteoarthritis. The main questions the trial aims to answer are: Compared to routine care, will patients with Knee OA receiving remote Tai Chi exhibit greater improvement …

50 - 100 years of age All Phase N/A
L Loes van Beers, MSc

Migration in Total Hip Arthroplasty With a Cemented BiMobile Cup: Better Stability With More Cement?

Objective: The main objective of this study is to compare the (early) migration of the cemented BiMobile cup at two year post-surgery between two different cup sizes after standard optimal reaming, and consequently adjusting the cement mantle into circa 2 or 4 mm, in patients with a primary cemented total …

65 years of age All Phase N/A
C Christine Pellegrini

Dose Response of Exercise for Arthritis Management

The purpose of the study is to see examine the effects of 3 different levels of physical activity (45 minutes/week, 90 minutes/week, or 150 minutes/week) on arthritis symptoms.

18 years of age All Phase N/A
M Monica Guma, M.D, PHD

Effect of Anti-inflammatory Diet in Osteoarthritis

In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metabolites. The current study will determine whether or not the addition of anti-inflammatory diet improves the clinical outcomes in participants with Osteoarthritis, and the …

18 years of age All Phase N/A
M Mark W Little, MD

Genicular Artery Embolisation for Knee Osteoarthritis II

This clinical study is designed as a double-blind sham controlled randomised trial with the option of sham group crossover to receive the GAE treatment at 6 months after unblinding. This study will determine if embolisation of abnormal neovasculature arising from branches of the genicular arteries reduces pain in patients with …

45 years of age All Phase N/A
K Kasper Staberg Madsen, MD

Metformin Treatment of Patients With Hand Osteoarthritis

To compare metformin (2 g daily), or maximum tolerated dose, for 16 weeks with placebo as a treatment of hand osteoarthritis symptoms.

18 years of age All Phase 3
M Maria Wilcke, MD, PhD

TRACE - Thumb Base Replacement Arthroplasty for Osteoarthritis.

Osteoarthritis in the base of the thumb is one of the most common forms of hand arthritis. It usually appears in middle age, particularly in women, and can cause significant pain and loss of function. Early treatment often includes splints, painkillers, joint protection techniques, or steroid injections. If these measures …

years of age All Phase N/A
B Basak Cigdem Karacay

Virtual Reality in Patients With Knee Osteoarthritis

One of the main challenges facing the therapist in the treatment of adhesive capsulitis is to motivate the patient throughout conventional therapy. As noted in a recent review, individuals are more interested in leisure activities rather than performing repetitive tasks during therapy. Virtual reality (VR) is a three-dimensional computer-aided programme …

40 - 85 years of age All Phase N/A
S Sara Larsson, MSc

Wrist Denervation Vs Exercise in Wrist Osteoarthritis

A randomized controlled trial comparing partial wrist denervation to a self-managed exercise therapy program in 140 patients with wrist osteoarthritis.

18 years of age All Phase N/A

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