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Osteoarthritis Clinical Trials

A listing of Osteoarthritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 536 clinical trials
O Ola Rolfson, MD

Implantation of Engineered Cartilage Grafts for Treatment of Patellofemoral Osteoarthritis Versus Surgical Comparators.

ENCANTO is a randomized, controlled, multi-center phase II clinical trial for the treatment of patellofemoral osteoarthritis (PFOA) with an Advanced Therapy Medicinal Product (ATMP), nasal chondrocyte-based tissue engineered cartilage (N-TEC) implantation in comparison with current standard of care depending on the stage of osteoarthritis. The goal of this phase II …

18 - 70 years of age All Phase 2
M Mario Lenza, PhD

Prognostic Factors in Zygapophyseal Osteoarthritis Infiltration: a Prospective Cohort Study

Magnet Resonance Image findings of facet osteoarthritis and patient characteristics are prognostic factors for improving or worsening the clinical outcome after treatment with facet infiltration.

18 years of age All Phase N/A
J Jonathan Kirschner, MD

PRP for Glenohumeral Osteoarthritis

The glenohumeral joint is the third most common large joint to be affected by OA. Conservative treatments include physical activity, corticosteroid injections, and medications. PRP is an emerging treatment that has shown efficacy in different musculoskeletal conditions. The use of PRP for glenohumeral OA has been described sparingly in the …

18 - 100 years of age All Phase 4

Thumb Proprioception in Trapeziometacarpal Osteoarthritis

This study looks at people who have osteoarthritis at the base of the thumb. It examines how well the thumb can sense its position and movement. The study has three goals: To compare these measurements between people with thumb base osteoarthritis and healthy people. To find out whether this ability …

25 - 75 years of age All Phase N/A
M Mostafa M Bahaa, PhD

Metformin Safety and Efficacy in Osteoarthritis.

Knee osteoarthritis (OA) is a chronic, painful disease associated with considerable morbidity, costs and disability. It is estimated that over a third of people aged over 60 have radiographic knee OA2 and over 50% of these with knee OA will go on to have a total knee replacement in their …

30 - 60 years of age All Phase 3
K Kaley Beall

ZILRETTA in Subjects With Shoulder Osteoarthritis

Primary Objective: To assess the efficacy of ZILRETTA on pain following an intra-articular (IA) injection in subjects with glenohumeral osteoarthritis (OA) relative to normal saline placebo Secondary Objective: To assess the efficacy of ZILRETTA on pain following an IA injection in subjects with glenohumeral OA relative to triamcinolone acetonide injectable …

50 - 80 years of age All Phase 3
F Fiona Howells

TSA vs RSA in Glenohumeral Osteoarthritis

This study will compare total shoulder arthroplasty (TSA) reverse shoulder arthroplasty (RSA) procedures, in the context of a prospective, randomized-controlled trial to determine the optimal treatment in patients 65 years of age and older, and equal to or less than 15 degrees of glenoid retroversion, who have glenohumeral osteoarthritis.

65 years of age All Phase N/A
C Chao Ma, MD

99Tc-MDP Treatment for Knee Osteoarthritis

Osteoarthritis (OA) of knee is the most common form of arthritis in the world1e, and it has received growing attention in the society because of the increase of old age population, disabled people, and medical expenses from this disease. 99Tc-MDP is effective for rheumatoid arthritis. Therefore, the investigators try to …

40 years of age All Phase N/A
M Marcel Jakob, MD

Treatment of Patellofemoral Osteoarthritis With Engineered Cartilage.

The purpose of this investigator-initiated study is to assess the efficacy of treating patellofemoral osteoarthritis with an Advanced Therapy Medicinal Product (ATMP), autologous nasal chondrocyte tissue engineered cartilage (N-TEC), in comparison with a standard therapy using platelet rich plasma injections. The engineered cartilage graft is obtained by culturing expanded autologous …

18 - 65 years of age All Phase 2
E Emma Judge

PRC With Meniscal Allograft Arthroplasty for Wrist Osteoarthritis

This study plans to learn more about the effect of adding tissue graft for wrist osteoarthritis reconstruction procedures. Previous studies have shown better allograft stability, and no documented foreign body reaction than with silicone and other synthetic materials.

30 - 80 years of age All Phase N/A

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