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Musculoskeletal Diseases Clinical Trials

A listing of Musculoskeletal Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 133 clinical trials

The Relationship Between Ergonomic Knowledge of Healthcare Professionals and Musculoskeletal Disorders

This study aims to investigate the relationship between the ergonomic awareness levels of Healthcare Workers and musculoskeletal disorders.

25 - 45 years of age All Phase N/A
X Xiaojuan Li, PhD

Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry

Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clinical need for robust assessment of early changes in cartilage health. Towards this goal, extensive efforts are ongoing to develop quantitative MRI for cartilage matrix analysis. …

18 - 50 years of age All Phase N/A

Use of an Integrated Orthotic and Rehabilitation Initiative for Treatment of Lower Extremity Musculoskeletal Disorders

The Intrepid Dynamic Exoskeletal Orthosis (IDEO) is a custom, energy storage and return ankle orthosis proven to improve functional ability when coupled with a customized high-intensity rehabilitation program. The Return to Performance (RTP) clinical pathway is the civilian version of the evidence-based Return To Run (RTR) clinical pathway. Together, the …

18 years of age All Phase N/A
J Julian F Scherer, MD

Gene Expression Profiles in Spinal Tuberculosis.

Tuberculosis (TB) is one of the top ten causes of death worldwide with approximately 10 million cases globally and 1.2 million deaths. Sub-Saharan Africa carries the highest burden of TB. South Africa has one of the highest HIV and TB rates worldwide with an HIV prevalence rate in adults of …

18 years of age All Phase N/A
P Pietro Randelli, Prof

EVOLUTION® Revision STEMMED CS Post Market Clinical Follow-up Study Protocol

MicroPort (MPO) is conducting this PMCF study to evaluate the safety and effectiveness of its EVOLUTION® Revision Tibial System and EVOLUTION® Revision STEMMED CS Femur with the EVOLUTION® MP CS Tibial Insert. This type of study is required by regulatory authorities for all devices that have been approved in Europe …

21 years of age All Phase N/A
J Joelle Williamson

WiTNNess - TNNT1 Myopathy Natural History Study

WiTNNess is designed to accurately document the natural course and variation of muscle disease caused by pathogenic changes of the TNNT1 gene. The primary aim of the study is to specify meaningful outcome measures for future clinical trials. WiTNNess is open to children and adults worldwide. Participants can choose to …

years of age All Phase N/A

The Application of Artificial Intelligence in Wrist and Hand Joint Ultrasound

To develop an AI system that can automatically identify standard sections and save images during wrist and hand joint ultrasound scans, while labeling key anatomical structures. To recruit sonographers untrained in musculoskeletal ultrasound, train them in wrist and hand joint scans, and compare their scanning speed and image quality when …

18 - 100 years of age All Phase N/A

Natural History, Pathogenesis and Outcome of Melorheostosis A Rare Osteosclerotic Disease

Background The rare disease melorheostosis causes bones to thicken. This may lead to pain, and can affect bones, joints, and muscles. Researchers want to learn more about the disease and how it progresses. Objective -To see what happens to people with melorheostosis over time and understand the causes of the …

18 - 90 years of age All Phase N/A
O Ozlem M Goker-Alpan, MD

Biomarkers Related to Bone in Pediatric Gaucher Disease

Aims of the observational study is to establish novel blood-based biomarkers for grading bone disease in pediatric patients with Gaucher disease (GD). Patients with clinically confirmed GD: deficient GCase enzyme activity and corresponding genetic analysis will be eligible for enrollment. Levels of Lyso-Gb1, chitotriosidase, and CCL18 will be established for …

5 - 21 years of age All Phase N/A
P Per Reidar Høiness, MD Phd

Wrist and Carpal Arthrodeses. A 1-year Follow-up Study.

This study at the Orthopedic Department, Drammen Hospital, examines the effectiveness and safety of various arthrodesis procedures in the wrist and carpus to relieve chronic pain and restore functional stability. Arthrodesis, which fuses two or more bones to eliminate joint mobility, is considered as a last resort when conservative treatments …

years of age All Phase N/A

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